PRKD2 and ATP1A3

		PRKD2	ATP1A3
Description		protein kinase D2	ATPase Na+/K+ transporting subunit alpha 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane	Photoreceptor Inner Segment Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Sodium:potassium-exchanging ATPase Complex Membrane Axon Organelle Membrane Neuronal Cell Body Membrane Neuronal Cell Body Synapse Photoreceptor Inner Segment Membrane Neuron To Neuron Synapse Extracellular Vesicle
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Protein Kinase C Binding Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity	Nucleotide Binding Amyloid-beta Binding P-type Sodium:potassium-exchanging Transporter Activity Protein Binding ATP Binding P-type Potassium Transmembrane Transporter Activity ATP Hydrolysis Activity Metal Ion Binding Protein-folding Chaperone Binding Steroid Hormone Binding
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Adaptive Immune Response Immune System Process Protein Phosphorylation Cell Adhesion Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Migration Sphingolipid Biosynthetic Process Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-8 Production Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Cell Adhesion Positive Regulation Of Transcription By RNA Polymerase II Vascular Endothelial Growth Factor Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Endothelial Tube Morphogenesis Regulation Of T Cell Apoptotic Process Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Intracellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Intracellular Monoatomic Cation Homeostasis Intracellular Potassium Ion Homeostasis Sodium Ion Export Across Plasma Membrane Regulation Of Resting Membrane Potential Cellular Response To Steroid Hormone Stimulus Cell Communication By Electrical Coupling Involved In Cardiac Conduction Proton Transmembrane Transport Response To Glycoside Cellular Response To Amyloid-beta Neuron Projection Maintenance Potassium Ion Import Across Plasma Membrane
Pathways		Sphingolipid de novo biosynthesis	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs			Ouabain Bisacodyl Tegoprazan
Diseases			Primary torsion dystonia (PTD)
GWAS		Aspartate aminotransferase levels ( 33547301) Chronic lymphocytic leukemia ( 18758461 28165464) Coronary artery disease ( 29212778) Eosinophil count ( 32888494) Heel bone mineral density ( 30598549) Post bronchodilator FEV1 ( 26634245) Primary sclerosing cholangitis ( 23603763 27992413)	Brain morphology (MOSTest) ( 32665545) Meat-related diet ( 32066663)
Interacting Genes		17 interacting genes: CASK DST GORASP1 GRIP1 HDAC7 HEY1 IFNAR1 MTF2 PDLIM7 PFDN1 PSG3 RARB RRBP1 RXRA SNRNP70 TGOLN2 VPS26C	2 interacting genes: ATXN1 CASP8
Entrez ID		25865	478
HPRD ID		09523	01666
Ensembl ID		ENSG00000105287	ENSG00000105409
Uniprot IDs		Q9BZL6	M0R116 P13637 Q53ES0
PDB IDs		2COA 3BGM 4NNX 4NNY	8D3U 8D3V 8D3W 8D3X 8D3Y
Enriched GO Terms of Interacting Partners?
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