LSM4 and SMU1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid)

		LSM4	SMU1
Description		LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated	SMU1 DNA replication regulator and spliceosomal factor
Image
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Spliceosomal Complex U6 SnRNP Cytosol Membrane Protein-containing Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome
	Molecular Function	RNA Binding Protein Binding U6 SnRNA Binding PH Domain Binding	Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process RNA Processing MRNA Processing RNA Splicing P-body Assembly	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Chronotype ( 30696823) Estimated glomerular filtration rate ( 30604766) Gastroesophageal reflux disease ( 31527586) Intraocular pressure ( 29617998) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Platelet distribution width ( 32888494) Red blood cell count ( 27863252 32888494) Reticulocyte count ( 32888494)	Aspartate aminotransferase levels ( 33547301) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		21 interacting genes: CALCOCO2 COX5B EXOSC8 GAS7 HOMEZ IKZF1 L3MBTL3 NMI PLEKHA5 PSTPIP1 RHOXF2 SLC22A2 SMIM14 SMN1 SMU1 SNRPE TOE1 TOP1 UBC XRN1 ZBTB10	12 interacting genes: CD2BP2 CEBPA CERT1 H2BC21 LSM4 LSM8 MRFAP1 MSS51 RASSF10 TLX3 UBC YBX1
Entrez ID		25804	55234
HPRD ID		06284	11588
Ensembl ID		ENSG00000130520	ENSG00000122692
Uniprot IDs		Q9Y4Z0 U3KQK1	A0MNN4 Q2TAY7
PDB IDs		3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG 8H6E 8H6J 8H6K 8H6L 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5	5O9Z 6AHD 6Q8F 6Q8I 6Q8J 8H6K 8H6L 8QO9 8QZS
Enriched GO Terms of Interacting Partners?		Nucleoplasm SMN-Sm Protein Complex RRNA Catabolic Process Nuclear MRNA Surveillance Precatalytic Spliceosome SnRNA 3'-end Processing	U4/U6 X U5 Tri-snRNP Complex Nucleoplasm Lsm2-8 Complex U6 SnRNP U6 SnRNA Binding RNA Splicing MRNA Processing Spliceosomal SnRNP Assembly RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding MRNA Metabolic Process Intermembrane Sphingolipid Transfer U2-type Precatalytic Spliceosome Response To Vitamin B2 C/EBP Complex Ceramide Transfer Activity CHOP-C/EBP Complex RNA Metabolic Process P-body RNA Processing Ribonucleoprotein Complex MiRNA Transport ER To Golgi Ceramide Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?