PGLS and BLMH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PGLS	BLMH
Description		6-phosphogluconolactonase	bleomycin hydrolase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Nucleus Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Hydrolase Activity 6-phosphogluconolactonase Activity	Aminopeptidase Activity Carboxypeptidase Activity Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Identical Protein Binding Cysteine-type Aminopeptidase Activity
	Biological Process	Carbohydrate Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Oxidative Branch	Protein Polyubiquitination Proteolysis Response To Xenobiotic Stimulus Response To Toxic Substance Homocysteine Catabolic Process
Pathways		Pentose phosphate pathway	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes		18 interacting genes: BLMH EWSR1 KLHL20 KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 MDFI NOTCH2NLA PLSCR1 POT1 RBPMS RCHY1 TERF1 TERF2IP	20 interacting genes: AP1M2 APP CDC42 CEBPA CYP2C8 ECSIT KBTBD7 MAST1 NTAQ1 NXF1 PDPK1 PGLS RNF32 RPL11 RPL29 TNPO2 TNPO3 TRIM47 TRIO UBE2I
Entrez ID		25796	642
HPRD ID		12001	03870
Ensembl ID		ENSG00000130313	ENSG00000108578
Uniprot IDs		A0A0K0K1K7 O95336	Q13867
PDB IDs			1CB5 2CB5 7V5L 7V5S 7V5T 7XF9
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Shelterin Complex Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase DNA Biosynthetic Process RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Telomeric D-loop Disassembly Positive Regulation Of Telomere Maintenance Telomeric Loop Disassembly Negative Regulation Of Chromosome Organization Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Identical Protein Binding Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Organization Negative Regulation Of DNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Chromosome, Telomeric Region Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Type II Interferon Binding Regulation Of Telomere Maintenance Via Telomere Lengthening Cysteine-type Aminopeptidase Activity Structural Constituent Of Skin Epidermis Lead Ion Binding Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of Chromosome Organization Positive Regulation Of Telomeric Loop Disassembly Protein K33-linked Ubiquitination Negative Regulation Of DNA Recombination At Telomere Cytosol Intermediate Filament Organization Phosphatidylserine Biosynthetic Process Mercury Ion Binding Phosphatidylserine Exposure On Apoptotic Cell Surface	Cytosol Cytoplasm Postsynapse Intracellular Transport Nuclear Transport Nucleocytoplasmic Transport Nuclear Import Signal Receptor Activity
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