DYNLT2B and CDKN2D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DYNLT2B	CDKN2D
Description		dynein light chain Tctex-type 2B	cyclin dependent kinase inhibitor 2D
Image
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Cytoplasmic Dynein Complex Cilium Axoneme Interphase Microtubule Organizing Center Ciliary Base Dynein Axonemal Particle	Nucleus Nucleoplasm Cytoplasm Cytosol Cyclin D2-CDK4 Complex
	Molecular Function	Protein Binding Dynein Intermediate Chain Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding
	Biological Process	Microtubule-based Movement Intraciliary Retrograde Transport Cilium Assembly Regulation Of Cilium Assembly Regulation Of Intraciliary Retrograde Transport	DNA Synthesis Involved In DNA Repair Sensory Perception Of Sound Negative Regulation Of Cell Population Proliferation Response To UV Negative Regulation Of Cell Growth Response To Retinoic Acid Response To Vitamin D Autophagic Cell Death Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Cell Cycle G1/S Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Intraflagellar transport	Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Cyclin D associated events in G1
Drugs
Diseases
GWAS			Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		9 interacting genes: ACTN2 BRCA1 CDKN2D CSNK2B GTF2F2 PPP2CB TK1 TRIM55 TRIM63	63 interacting genes: APP BRCA1 BTG1 C1orf94 CCND3 CDK4 CDK6 CFAP90 CGGBP1 CTBP1 DDIT4L DMRTB1 DYNLT2B EIF4G1 FAM228A FAM86C1P FHL3 GATAD2B GLYR1 GORASP2 GSC2 HSD17B14 IKZF3 INCA1 KRT75 LNX1 LONRF1 LSM3 MEI4 MEOX2 MSS51 MTF2 NDUFB7 NIF3L1 NME4 NMI NR4A1 NR4A2 NR4A3 PICK1 PRDX5 PRIMPOL PSMA1 QKI REL RUFY4 SAXO1 SDCBP SH3GLB1 SH3GLB2 TBC1D17 TEX11 THAP1 TSG101 TSGA10IP UQCC2 VGLL1 YPEL3 ZBTB32 ZNF396 ZNF620 ZNF688 ZNF774
Entrez ID		255758	1032
HPRD ID		14554	02957
Ensembl ID		ENSG00000213123	ENSG00000129355
Uniprot IDs		Q8WW35	P55273
PDB IDs		8J07 8RGI	1BD8 1BI8
Enriched GO Terms of Interacting Partners?		Titin Binding Transmembrane Transporter Binding Titin Z Domain Binding Structural Constituent Of Postsynaptic Actin Cytoskeleton Regulation Of Cytoskeleton Organization Channel Activator Activity Metal Ion Binding Microspike Assembly Phospholipase C-activating Angiotensin-activated Signaling Pathway Actin Filament Uncapping FATZ Binding Z Disc Identical Protein Binding LIM Domain Binding Protein Modification Process Negative Regulation Of Centriole Replication BRCA1-B Complex Negative Regulation Of Cell Growth Histone H2AK127 Ubiquitin Ligase Activity Negative Regulation Of Small Molecule Metabolic Process Nuclear Ubiquitin Ligase Complex Cellular Response To Indole-3-methanol BRCA1-C Complex Nucleus Negative Regulation Of Mitotic Cell Cycle Phase Transition Ubiquitin Protein Ligase Activity Regulation Of Intracellular Signal Transduction Histone H2AK129 Ubiquitin Ligase Activity Macromolecule Metabolic Process Response To Indole-3-methanol BRCA1-BARD1 Complex Protein Ubiquitination Cyclin D2-CDK4 Complex DNA Biosynthetic Process Autophagic Cell Death Positive Regulation Of Activin Receptor Signaling Pathway Protein Kinase CK2 Complex Negative Regulation Of Viral Life Cycle Symbiont-mediated Disruption Of Host Cell PML Body Release From Viral Latency RNA Polymerase II, Holoenzyme Transcription Factor TFIIF Complex Regulation Of Neurofibrillary Tangle Assembly DNA Synthesis Involved In Mitotic DNA Replication Thymidine Metabolic Process Thymidine Biosynthetic Process Thymidine Kinase Activity Diapedesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Corticotropin-releasing Hormone Stimulus Regulation Of Transcription By RNA Polymerase II Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Protein Binding Regulation Of Macromolecule Biosynthetic Process DNA Binding Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Cyclin D3-CDK6 Complex Cyclin D3-CDK4 Complex Regulation Of Type B Pancreatic Cell Proliferation Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Glucocorticoid Receptor Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Cycle Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Regulation Of Organelle Assembly Regulation Of Primary Metabolic Process Nucleus Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Chromatin Cyclin-dependent Protein Serine/threonine Kinase Activity Identical Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Extracellular Exosome Assembly Negative Regulation Of Metabolic Process Cyclin Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Mitotic Cell Cycle Cyclin-dependent Protein Kinase Holoenzyme Complex Negative Regulation Of Type I Interferon Production DNA-binding Transcription Factor Activity Nuclear Receptor Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?