DYNLT2B

Description		dynein light chain Tctex-type 2B
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GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Cytoplasmic Dynein Complex Cilium Axoneme Interphase Microtubule Organizing Center Ciliary Base Dynein Axonemal Particle
	Molecular Function	Protein Binding Dynein Intermediate Chain Binding
	Biological Process	Microtubule-based Movement Intraciliary Retrograde Transport Cilium Assembly Regulation Of Cilium Assembly Regulation Of Intraciliary Retrograde Transport
Pathways		Intraflagellar transport
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: ACTN2 BRCA1 CDKN2D CSNK2B GTF2F2 PPP2CB TK1 TRIM55 TRIM63
Entrez ID		255758
HPRD ID		14554
Ensembl ID		ENSG00000213123
Uniprot IDs		Q8WW35
PDB IDs		8J07 8RGI
Enriched GO Terms of Interacting Partners?		Titin Binding Transmembrane Transporter Binding Titin Z Domain Binding Structural Constituent Of Postsynaptic Actin Cytoskeleton Regulation Of Cytoskeleton Organization Channel Activator Activity Metal Ion Binding Microspike Assembly Phospholipase C-activating Angiotensin-activated Signaling Pathway Actin Filament Uncapping FATZ Binding Z Disc Identical Protein Binding LIM Domain Binding Protein Modification Process Negative Regulation Of Centriole Replication BRCA1-B Complex Negative Regulation Of Cell Growth Histone H2AK127 Ubiquitin Ligase Activity Negative Regulation Of Small Molecule Metabolic Process Nuclear Ubiquitin Ligase Complex Cellular Response To Indole-3-methanol BRCA1-C Complex Nucleus Negative Regulation Of Mitotic Cell Cycle Phase Transition Ubiquitin Protein Ligase Activity Regulation Of Intracellular Signal Transduction Histone H2AK129 Ubiquitin Ligase Activity Macromolecule Metabolic Process Response To Indole-3-methanol BRCA1-BARD1 Complex Protein Ubiquitination Cyclin D2-CDK4 Complex DNA Biosynthetic Process Autophagic Cell Death Positive Regulation Of Activin Receptor Signaling Pathway Protein Kinase CK2 Complex Negative Regulation Of Viral Life Cycle Symbiont-mediated Disruption Of Host Cell PML Body Release From Viral Latency RNA Polymerase II, Holoenzyme Transcription Factor TFIIF Complex Regulation Of Neurofibrillary Tangle Assembly DNA Synthesis Involved In Mitotic DNA Replication Thymidine Metabolic Process Thymidine Biosynthetic Process Thymidine Kinase Activity Diapedesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy
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