ADAM2 and CLGN

Number of citations of the paper that reports this interaction (PMID 11784061)
17

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		ADAM2	CLGN
Gene Name		ADAM metallopeptidase domain 2	calmegin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Metalloendopeptidase Activity Integrin Binding Metallopeptidase Activity Zinc Ion Binding	Calcium Ion Binding Protein Binding Involved In Protein Folding Unfolded Protein Binding
	Biological Process	Proteolysis Cell Adhesion Single Fertilization Binding Of Sperm To Zona Pellucida Fusion Of Sperm To Egg Plasma Membrane Visual Learning Adult Behavior Multicellular Organism Reproduction	Protein Folding Protein Complex Assembly Single Fertilization Binding Of Sperm To Zona Pellucida
Pathways		Interaction With The Zona Pellucida Fertilization
Drugs
Diseases
GWAS			Select biomarker traits ( 17903293)
Protein-Protein Interactions		2 interactors: CD9 CLGN	3 interactors: ADAM2 GDE1 XK
Entrez ID		2515	1047
HPRD ID		03322	03513
Ensembl ID		ENSG00000104755	ENSG00000153132
Uniprot IDs		B4DWY7 Q6P2G0 Q99965	O14967
PDB IDs
Enriched GO Terms of Interacting Partners?		Single Fertilization Fertilization Response To Water Deprivation Sexual Reproduction Fusion Of Sperm To Egg Plasma Membrane Paranodal Junction Assembly Plasma Membrane Fusion Reproduction Myelin Assembly Single Organism Reproductive Process Reproductive Process Oligodendrocyte Development Binding Of Sperm To Zona Pellucida Sperm-egg Recognition Cell-cell Recognition Platelet Degranulation Oligodendrocyte Differentiation Cellular Component Assembly Glial Cell Development Cell-cell Junction Assembly Cell Recognition Membrane Fusion Myelination Axon Ensheathment Glial Cell Differentiation Platelet Activation Cell Junction Assembly Pathogenesis Cell-cell Junction Organization	Cellular Magnesium Ion Homeostasis Regulation Of Axon Diameter Regulation Of Cell Projection Size Magnesium Ion Homeostasis Fusion Of Sperm To Egg Plasma Membrane Plasma Membrane Fusion Skeletal Muscle Fiber Development Glycerol Metabolic Process Myotube Cell Development
Tagcloud ?		adam1a adam3 calmegin calnexin calr calr3 calreticulin calsperin canx chaperones clgn client contraception contrasting cooperate fertility fertilization germ infertile infertility lectin nascent oviduct pave pellucida sperm unexplained uterus zona	adam1a adam2 adam3 calmegin calnexin calr calr3 calreticulin calsperin canx chaperones client contraception contrasting cooperate fertility fertilization germ infertile infertility lectin nascent oviduct pave pellucida sperm unexplained uterus zona
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		adam1a adam2 adam3 calmegin calnexin calr calr3 calreticulin calsperin canx chaperones clgn client contraception contrasting cooperate fertility fertilization germ infertile infertility lectin nascent oviduct pave pellucida sperm unexplained uterus zona