IL17RA and POTEH

Data Source: HiPPIP (Novel)

		IL17RA	POTEH
Name		interleukin 17 receptor A	POTE ankyrin domain family member H
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane	None
	Molecular Function	Signaling Receptor Binding Protein Binding Interleukin-17 Receptor Activity	None
	Biological Process	Adaptive Immune Response Immune System Process Inflammatory Response Cell Surface Receptor Signaling Pathway Response To Virus Protein Catabolic Process Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-23 Production Positive Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-6 Production Interleukin-17A-mediated Signaling Pathway Innate Immune Response Positive Regulation Of Inflammatory Response Defense Response To Fungus Granulocyte Chemotaxis Fibroblast Activation T-helper 17 Type Immune Response Interleukin-17-mediated Signaling Pathway Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production	None
Pathways		Interleukin-17 signaling SARS-CoV-2 activates/modulates innate and adaptive immune responses	None
Diseases		Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)	None
GWAS		Blood protein levels ( 30072576 ) Eosinophil count ( 32888494 ) Eosinophil percentage of white cells ( 32888494 ) Granulocyte percentage of myeloid white cells ( 27863252 ) Heschl's gyrus morphology ( 25130324 ) Lymphocyte percentage of white cells ( 32888494 ) Monocyte count ( 27863252 32888494 ) Monocyte percentage of white cells ( 27863252 32888494 ) Myeloid white cell count ( 27863252 ) Neutrophil count ( 32888494 ) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600 ) White blood cell count ( 27863252 32888494 )	No GWAS studies recorded
Novel Interactors		5 novel interactors: BCL2L13 BID POTEH PTPRT TESK1	2 novel interactors: IL17RA TUBA8
Interacting Genes		2 interacting genes: IL17A MTDH	None recorded
Entrez ID		23765	23784
HPRD ID		10399	16403
Ensembl ID		ENSG00000177663	ENSG00000198062
Uniprot IDs		Q96F46	Q6S545
PDB IDs		3JVF 4HSA 4NUX 5N9B 5NAN 7UWL 7UWM 7UWN 7ZAN	Not available
GO Terms Enriched among Interactors		None	Fibroblast Activation Positive Regulation Of Interleukin-23 Production Interleukin-17 Receptor Activity T-helper 17 Type Immune Response Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Interleukin-17A-mediated Signaling Pathway Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Regulation Of Interleukin-23 Production Interleukin-17-mediated Signaling Pathway Positive Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-13 Production Regulation Of Interleukin-5 Production Positive Regulation Of Cytokine Production Involved In Inflammatory Response