IL17RA and POTEH

		IL17RA	POTEH
Description		interleukin 17 receptor A	POTE ankyrin domain family member H
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Interleukin-17 Receptor Activity
	Biological Process	Adaptive Immune Response Immune System Process Inflammatory Response Cell Surface Receptor Signaling Pathway Response To Virus Protein Catabolic Process Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-23 Production Positive Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-6 Production Interleukin-17A-mediated Signaling Pathway Innate Immune Response Positive Regulation Of Inflammatory Response Defense Response To Fungus Granulocyte Chemotaxis Fibroblast Activation T-helper 17 Type Immune Response Interleukin-17-mediated Signaling Pathway Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production
Pathways		Interleukin-17 signaling SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases		Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS		Blood protein levels ( 30072576) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Granulocyte percentage of myeloid white cells ( 27863252) Heschl's gyrus morphology ( 25130324) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600) White blood cell count ( 27863252 32888494)
Interacting Genes		2 interacting genes: IL17A MTDH
Entrez ID		23765	23784
HPRD ID		10399	16403
Ensembl ID		ENSG00000177663	ENSG00000198062
Uniprot IDs		Q96F46	Q6S545
PDB IDs		3JVF 4HSA 4NUX 5N9B 5NAN 7UWL 7UWM 7UWN 7ZAN
Enriched GO Terms of Interacting Partners?			Fibroblast Activation Positive Regulation Of Interleukin-23 Production Interleukin-17 Receptor Activity T-helper 17 Type Immune Response Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Interleukin-17A-mediated Signaling Pathway Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Regulation Of Interleukin-23 Production Interleukin-17-mediated Signaling Pathway Positive Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-13 Production Regulation Of Interleukin-5 Production Positive Regulation Of Cytokine Production Involved In Inflammatory Response
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