IL17RA

Name	interleukin 17 receptor A
Structure
Novel Interactors	5 novel interactors: BCL2L13 BID POTEH PTPRT TESK1
Interactors	2 interactors: IL17A MTDH
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Interleukin-17 Receptor Activity
	Biological Process	Adaptive Immune Response Immune System Process Inflammatory Response Cell Surface Receptor Signaling Pathway Response To Virus Protein Catabolic Process Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-23 Production Positive Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-6 Production Interleukin-17A-mediated Signaling Pathway Innate Immune Response Positive Regulation Of Inflammatory Response Defense Response To Fungus Granulocyte Chemotaxis Fibroblast Activation T-helper 17 Type Immune Response Interleukin-17-mediated Signaling Pathway Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production
Pathways	Interleukin-17 signaling SARS-CoV-2 activates/modulates innate and adaptive immune responses
Diseases	Chronic Mucocutaneous Candidiasis (CMC); Familial candidiasis (CANDF)
GWAS	Blood protein levels ( 30072576 ) Eosinophil count ( 32888494 ) Eosinophil percentage of white cells ( 32888494 ) Granulocyte percentage of myeloid white cells ( 27863252 ) Heschl's gyrus morphology ( 25130324 ) Lymphocyte percentage of white cells ( 32888494 ) Monocyte count ( 27863252 32888494 ) Monocyte percentage of white cells ( 27863252 32888494 ) Myeloid white cell count ( 27863252 ) Neutrophil count ( 32888494 ) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600 ) White blood cell count ( 27863252 32888494 )
Entrez ID	23765
HPRD ID	10399
Ensembl ID	ENSG00000177663
Uniprot IDs	Q96F46
PDB IDs	3JVF 4HSA 4NUX 5N9B 5NAN 7UWL 7UWM 7UWN 7ZAN