PRND and RPSA

Number of citations of the paper that reports this interaction (PMID 15246873)
2

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		PRND	RPSA
Gene Name		prion protein 2 (dublet)	ribosomal protein SA
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Anchored Component Of Membrane	Nucleus Cytoplasm Cytosol Plasma Membrane Membrane Cytosolic Small Ribosomal Subunit 90S Preribosome Extracellular Vesicular Exosome
	Molecular Function		Structural Constituent Of Ribosome Laminin Receptor Activity Protein Binding Ribosome Binding Laminin Binding Poly(A) RNA Binding
	Biological Process	Protein Homooligomerization	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Export From Nucleus Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Cell Adhesion Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: RPSA	27 interactors: ABCD1 ACADVL ACD ANKH C6orf106 CALM2 CBX5 CLEC4G CSF2RA DCTN6 GNMT HBG2 HNRNPD IL7R ITGA6 KARS LAMA2 NKX3-1 POT1 PRND PROS1 RNF114 RPS21 SLC2A5 SUMO4 TINF2 TRIB3
Entrez ID		23627	3921
HPRD ID		05039	01038
Ensembl ID		ENSG00000171864	ENSG00000168028
Uniprot IDs		Q9UKY0	P08865
PDB IDs		1LG4	3BCH 3J3A
Enriched GO Terms of Interacting Partners?		RRNA Export From Nucleus Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Transport RRNA 3'-end Processing Ribosomal Small Subunit Assembly Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Ribosome Assembly Maturation Of SSU-rRNA Ribosomal Small Subunit Biogenesis RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Export From Nucleus Viral Transcription Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum RNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis Nuclear Export Protein Localization To Endoplasmic Reticulum RRNA Processing RRNA Metabolic Process RNA Transport Translational Termination Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Protein Targeting To Membrane Ribonucleoprotein Complex Assembly Translational Elongation RNA Catabolic Process Ribosome Biogenesis Cellular Protein Complex Disassembly Viral Life Cycle Protein Complex Disassembly Establishment Of Protein Localization To Membrane Translational Initiation Nucleocytoplasmic Transport Nuclear Transport Nucleic Acid Phosphodiester Bond Hydrolysis Ribonucleoprotein Complex Biogenesis Establishment Of Protein Localization To Organelle Protein Localization To Membrane Protein Targeting Aromatic Compound Catabolic Process NcRNA Metabolic Process	Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Protein Localization To Chromosome, Telomeric Region Telomere Capping Negative Regulation Of DNA Replication Positive Regulation Of Telomerase Activity Positive Regulation Of Transferase Activity Telomere Maintenance Positive Regulation Of Telomere Maintenance Negative Regulation Of Fatty Acid Biosynthetic Process Blood Coagulation Hemostasis Negative Regulation Of Chromosome Organization Regulation Of Telomerase Activity Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Biosynthetic Process Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Body Fluid Levels Regulation Of DNA Replication Wound Healing Negative Regulation Of Biosynthetic Process Protein Localization To Chromosome Positive Regulation Of DNA Metabolic Process Cellular Response To Organic Substance Telomere Maintenance Via Telomere Lengthening Regulation Of Fatty Acid Biosynthetic Process Response To Wounding Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Lipid Biosynthetic Process Negative Regulation Of Protein ADP-ribosylation Lysyl-tRNA Aminoacylation Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Peroxisomal Long-chain Fatty Acid Import Fructose Transport Regulation Of DNA Biosynthetic Process Fatty Acid Beta-oxidation Regulation Of Chromosome Organization Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Metabolic Process Glycogen Metabolic Process Response To Stress Regulation Of Protein ADP-ribosylation Inorganic Diphosphate Transport Positive Regulation Of Androgen Secretion Interleukin-7-mediated Signaling Pathway
Tagcloud ?		artificial ataxia bindings biochemically brn counteraction doppel dpl electrophoretic gc hypothesize infertility n2a prion prnp productive prp purkinje regulations reproduction sp1 sp3 spermatogenic spg stimulatory structurally telangiectasia testis usf	abolish arg357 bonds confer conformational crystal elusive exhibits exquisite hydrogen hydrophobic insights lys303 mode mtb phe307 phe310 poa pyrazinamide pyrazinoic pza questions reveals ribosomal s1 shortening tb terminus tmrna
Tagcloud (Difference) ?		artificial ataxia bindings biochemically brn counteraction doppel dpl electrophoretic gc hypothesize infertility n2a prion prnp productive prp purkinje regulations reproduction sp1 sp3 spermatogenic spg stimulatory structurally telangiectasia testis usf	abolish arg357 bonds confer conformational crystal elusive exhibits exquisite hydrogen hydrophobic insights lys303 mode mtb phe307 phe310 poa pyrazinamide pyrazinoic pza questions reveals ribosomal s1 shortening tb terminus tmrna
Tagcloud (Intersection) ?