ZIM2 and KRTAP10-6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZIM2	KRTAP10-6
Description		zinc finger imprinted 2	keratin associated protein 10-6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway	Keratinization
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Triglyceride levels ( 32203549)
Interacting Genes		32 interacting genes: AQP1 BAG4 CATSPER1 CCDC120 CRYAA EPM2AIP1 FAM161A GLYCTK HOXA1 IL16 KRTAP10-6 KRTAP10-7 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP3-2 LIMS1 MDFI MID2 MKRN3 PATZ1 PHF1 POLR1C POU6F2 SCNM1 TCHP TEKT4 TNS2 TTC23 USP2 ZNF383 ZNF587	87 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-1 KRTAP10-5 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SLC33A2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1
Entrez ID		23619	386674
HPRD ID		10321	11192
Ensembl ID		ENSG00000269699	ENSG00000188155
Uniprot IDs		A0A8I5KWX0 Q9NZV7	P60371
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Identical Protein Binding	Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Tissue Development Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Keratin Filament Hair Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Wnt Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Diaphragm Development Cartilage Morphogenesis Regulation Of Macromolecule Metabolic Process
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