RPL28 and TMEM230

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		RPL28	TMEM230
Gene Name		ribosomal protein L28	transmembrane protein 230
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Dendrite Cytoplasmic Ribonucleoprotein Granule Cell Body Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CCNDBP1 MAP2K5 SGOL1 SMAD4 STAU1 TMEM230	4 interactors: ARL4D RPL28 TMEM9 VKORC1
Entrez ID		6158	29058
HPRD ID		04702	12762
Ensembl ID		ENSG00000108107	ENSG00000089063
Uniprot IDs		H0YKD8 P46779	Q96A57
PDB IDs		3J3B
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production ERK5 Cascade Nephrogenic Mesenchyme Morphogenesis Positive Regulation By Virus Of Viral Protein Levels In Host Cell Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Negative Regulation Of Interleukin-8 Biosynthetic Process Endocardial Cell Differentiation Centriole-centriole Cohesion Negative Regulation Of Heterotypic Cell-cell Adhesion Cellular Response To Laminar Fluid Shear Stress Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Formation Of Anatomical Boundary Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Endothelial Cell Activation Regulation Of Transforming Growth Factor Beta2 Production Regulation Of Cell Growth Positive Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Valve Formation Sebaceous Gland Development Intracellular MRNA Localization Regulation Of Interleukin-8 Biosynthetic Process Attachment Of Spindle Microtubules To Kinetochore Somite Rostral/caudal Axis Specification Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Brainstem Development SMAD Protein Complex Assembly Regulation Of SMAD Protein Import Into Nucleus Atrioventricular Canal Development Negative Regulation Of Interleukin-8 Production Regulation Of Hair Follicle Development Heart Valve Formation Metanephric Mesenchyme Development Endocardial Cushion Formation Endocardium Development Regulation Of Cell Migration Involved In Sprouting Angiogenesis Cellular Response To Fluid Shear Stress Atrioventricular Valve Morphogenesis Response To Laminar Fluid Shear Stress Regulation Of Sprouting Angiogenesis Regulation Of Hair Cycle Negative Regulation Of Blood Vessel Endothelial Cell Migration Endocardial Cushion Morphogenesis Atrioventricular Valve Development Heart Development Positive Regulation Of Viral Genome Replication Cardiac Epithelial To Mesenchymal Transition Regulation Of Cytokine Production Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
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