NCAPH and CAPG

Number of citations: 36 (PubMedID 11694586)
Data Source: HPRD (in vitro, in vivo)

		NCAPH	CAPG
Name		non-SMC condensin I complex subunit H	capping actin protein, gelsolin like
Structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Condensin Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Membrane	Ruffle Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Centriole F-actin Capping Protein Complex Actin Cytoskeleton Lamellipodium Melanosome Cell Projection Extracellular Exosome Mitotic Spindle Flemming Body
	Molecular Function	Chromatin Binding Protein Binding	Actin Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein Domain Specific Binding Protein-containing Complex Binding Cadherin Binding Actin Filament Binding
	Biological Process	Mitotic Chromosome Condensation Female Meiotic Nuclear Division Meiotic Chromosome Condensation Chromosome Condensation Meiotic Chromosome Segregation Cell Division Female Meiosis Chromosome Separation Positive Regulation Of Chromosome Segregation Positive Regulation Of Chromosome Separation Positive Regulation Of Chromosome Condensation	Central Nervous System Development Actin Polymerization Or Depolymerization Extracellular Matrix Disassembly Cell Projection Assembly Actin Filament Severing Barbed-end Actin Filament Capping Actin Filament Capping Protein-containing Complex Assembly Positive Regulation Of Podosome Assembly
Pathways		Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes	None
GWAS		Diastolic blood pressure ( 27618452 ) Monocyte count ( 32888494 )	Blood protein levels ( 30072576 )
Interacting Genes		6 interacting genes: AURKB CAPG CDK1 H2AC20 H2AZ1 TBP	4 interacting genes: CEBPA NCAPH SIAH1 TP53
Entrez ID		23397	822
HPRD ID		03820	01088
Ensembl ID		ENSG00000121152	ENSG00000042493
Uniprot IDs		B4DRG7 Q15003	B2R9S4 P40121 V9HW69
PDB IDs		6IGX	1J72 1JHW
GO Terms Enriched among Interactors		Positive Regulation Of Mitotic Sister Chromatid Segregation Regulation Of Metaphase Plate Congression Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Protein Localization To Kinetochore RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Attachment Of Spindle Microtubules To Kinetochore Chromosome Positive Regulation Of Chromosome Segregation Protein Localization To Chromosome, Centromeric Region Spindle Microtubule Cell Cycle G2/M Phase Transition Euchromatin Negative Regulation Of Cell Cycle G2/M Phase Transition Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Pronuclear Fusion Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Structural Constituent Of Chromatin Regulation Of Protein Depolymerization Positive Regulation Of Organelle Organization Protein Localization To Chromosome Mitotic DNA-templated DNA Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Sister Chromatid Segregation Cyclin B1-CDK1 Complex Positive Regulation Of Chromosome Organization Cyclin A1-CDK1 Complex Regulation Of Cell Cycle G2/M Phase Transition Cyclin A2-CDK1 Complex Nucleosome Mitotic Sister Chromatid Biorientation Repair Of Mitotic Kinetochore Microtubule Attachment Defect Regulation Of Protein-containing Complex Disassembly Microtubule Cytoskeleton Organization Involved In Mitosis Mitotic Spindle Chromatin Remodeling Mitotic DNA Replication DNA Synthesis Involved In Mitotic DNA Replication Regulation Of Chromosome Segregation Cyclin-dependent Protein Kinase Activity Heterochromatin Formation Regulation Of Schwann Cell Differentiation Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Cell Cycle Phase Transition TFIIB-class Transcription Factor Binding Mitotic Cytokinesis Checkpoint Signaling Sister Chromatid Biorientation Negative Regulation Of Gene Expression, Epigenetic Midbody Thymidine Biosynthetic Process	Negative Regulation Of Stem Cell Proliferation Chromatin Binding Positive Regulation Of DNA-templated Transcription Initiation Stem Cell Proliferation Regulation Of Stem Cell Proliferation Cellular Response To Xenobiotic Stimulus Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Neuron Apoptotic Process Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition CHOP-C/EBP Complex Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Nuclear Matrix Embryonic Organ Development Response To Vitamin B2 C/EBP Complex Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Pentose-phosphate Shunt Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Female Meiosis Chromosome Separation White Fat Cell Proliferation Regulation Of Cell Cycle Positive Regulation Of Thymocyte Apoptotic Process Response To Actinomycin D T Cell Proliferation Involved In Immune Response Meiotic Chromosome Separation Transcription Regulator Complex Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Histone Deacetylase Regulator Activity Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Chromosome Organization Regulation Of G1 To G0 Transition Glial Cell Apoptotic Process Cellular Response To UV-C ATP-dependent DNA/DNA Annealing Activity Female Meiosis Chromosome Segregation Transcription Cis-regulatory Region Binding Mitochondrion Organization