CAPG

Name	capping actin protein, gelsolin like
Structure
Interactors	4 interactors: CEBPA NCAPH SIAH1 TP53
GO Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm Centriole F-actin Capping Protein Complex Actin Cytoskeleton Lamellipodium Melanosome Cell Projection Extracellular Exosome Mitotic Spindle Flemming Body
	Molecular Function	Actin Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein Domain Specific Binding Protein-containing Complex Binding Cadherin Binding Actin Filament Binding
	Biological Process	Central Nervous System Development Actin Polymerization Or Depolymerization Extracellular Matrix Disassembly Cell Projection Assembly Actin Filament Severing Barbed-end Actin Filament Capping Actin Filament Capping Protein-containing Complex Assembly Positive Regulation Of Podosome Assembly
GWAS	Blood protein levels ( 30072576 )
Entrez ID	822
HPRD ID	01088
Ensembl ID	ENSG00000042493
Uniprot IDs	B2R9S4 P40121 V9HW69
PDB IDs	1J72 1JHW
GO Terms Enriched among Interactors ?	Negative Regulation Of Stem Cell Proliferation Chromatin Binding Positive Regulation Of DNA-templated Transcription Initiation Stem Cell Proliferation Regulation Of Stem Cell Proliferation Cellular Response To Xenobiotic Stimulus Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Neuron Apoptotic Process Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition CHOP-C/EBP Complex Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Nuclear Matrix Embryonic Organ Development Response To Vitamin B2 C/EBP Complex Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Pentose-phosphate Shunt Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Female Meiosis Chromosome Separation White Fat Cell Proliferation Regulation Of Cell Cycle Positive Regulation Of Thymocyte Apoptotic Process Response To Actinomycin D T Cell Proliferation Involved In Immune Response Meiotic Chromosome Separation Transcription Regulator Complex Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Histone Deacetylase Regulator Activity Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Chromosome Organization Regulation Of G1 To G0 Transition Glial Cell Apoptotic Process Cellular Response To UV-C ATP-dependent DNA/DNA Annealing Activity Female Meiosis Chromosome Segregation Transcription Cis-regulatory Region Binding Mitochondrion Organization