TUT4 and YBX2

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		TUT4	YBX2
Description		terminal uridylyl transferase 4	Y-box binding protein 2
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GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Nucleus Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Transferase Activity Nucleotidyltransferase Activity MiRNA Binding Metal Ion Binding RNA Uridylyltransferase Activity	Nucleic Acid Binding DNA Binding RNA Binding
	Biological Process	Oocyte Maturation MiRNA Metabolic Process MiRNA Catabolic Process Stem Cell Population Maintenance Regulatory NcRNA-mediated Gene Silencing Pre-miRNA Processing RNA 3'-end Processing Histone MRNA Catabolic Process Transposable Element Silencing By MRNA Destabilization Polyuridylation-dependent MRNA Catabolic Process	Transcription By RNA Polymerase II Spermatogenesis Translational Attenuation Regulation Of Gene Expression Oocyte Development Positive Regulation Of Cold-induced Thermogenesis
Pathways		Deadenylation of mRNA Zygotic genome activation (ZGA) Z-decay: degradation of maternal mRNAs by zygotically expressed factors
Drugs
Diseases
GWAS
Interacting Genes		13 interacting genes: CPSF7 FXR2 MIR143 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7C MIRLET7D MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I YBX2	54 interacting genes: MIR1-1 MIR1-2 MIR106B MIR10B MIR128-1 MIR128-2 MIR138-2 MIR141 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR200A MIR200B MIR200C MIR205 MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-3 MIR93 MIRLET7A1 MIRLET7A2 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP2 RBM22 SUPT5H TUT4
Entrez ID		23318	51087
HPRD ID		15700	18311
Ensembl ID		ENSG00000134744	ENSG00000006047
Uniprot IDs		Q5TAX3	A0A384MDP4 Q9Y2T7
PDB IDs		6IW6 8OST	7F3I 7F3J 7F3K 7F3L
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MRNA Destabilization RNA Destabilization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of MRNA Catabolic Process MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By MRNA Destabilization Positive Regulation Of MRNA Metabolic Process Extracellular Space Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Interleukin-8 Production Negative Regulation Of Interleukin-10 Production Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Translation Regulation Of Endothelial Cell Migration Calcidiol 1-monooxygenase Activity Secalciferol 1-monooxygenase Activity Cellular Response To Amyloid-beta Regulation Of Multicellular Organismal Process Positive Regulation Of Catabolic Process Regulation Of Cell Migration Involved In Sprouting Angiogenesis Response To Amyloid-beta	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Extracellular Vesicle Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Metabolic Process Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility MRNA Destabilization RNA Destabilization Negative Regulation Of Locomotion Positive Regulation Of MRNA Catabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Extracellular Space Positive Regulation Of MRNA Metabolic Process Regulation Of Endothelial Cell Migration Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Translation Regulation Of Connective Tissue Replacement Regulation Of MRNA Stability Regulation Of Cell Migration Regulation Of RNA Stability Regulation Of Cell Motility Negative Regulation Of Multicellular Organismal Process Regulation Of Locomotion Negative Regulation Of Protein Metabolic Process Positive Regulation Of Tissue Remodeling
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