DIP2A and BACE2

		DIP2A	BACE2
Description		disco interacting protein 2 homolog A	beta-secretase 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Plasma Membrane Cell Surface Membrane Cell Projection Dendritic Spine Synapse	Endosome Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Plasma Membrane Membrane Melanosome Membrane Melanosome
	Molecular Function	Acetate-CoA Ligase Activity Protein Binding Ligase Activity	Aspartic-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity
	Biological Process	Acetyl-CoA Biosynthetic Process Nervous System Development Negative Regulation Of Gene Expression Dendritic Spine Morphogenesis Positive Regulation Of Peptidyl-lysine Acetylation	Proteolysis Membrane Protein Ectodomain Proteolysis Protein Processing Peptide Hormone Processing Melanosome Organization Glucose Homeostasis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Amyloid-beta Metabolic Process
Pathways
Drugs
Diseases
GWAS		Anti-saccade response ( 29064472) Lymphocyte count ( 27863252 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) Pulse pressure ( 30224653) White blood cell count ( 32888494)	Adult body size ( 32376654) Body mass index ( 25673413) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Elevated fasting plasma glucose ( 30004843) Glycemic traits (pregnancy) ( 23903356) Systemic lupus erythematosus ( 32771030)
Interacting Genes		20 interacting genes: ADAMTSL4 ATOSB CCDC33 CEP44 DAB2 DLX2 DSCAM GPATCH2L IQUB JMJD6 MBIP PSME3 PTPN3 SORBS3 STAC3 TLE5 TMCC2 TRIM39 TRIP13 ZBTB43	5 interacting genes: APP GGA1 GGA2 PCM1 SNRNP70
Entrez ID		23181	25825
HPRD ID		07611	05744
Ensembl ID		ENSG00000160305	ENSG00000182240
Uniprot IDs		A0A494C143 Q14689 Q96NX2	Q9Y5Z0
PDB IDs			2EWY 3ZKG 3ZKI 3ZKM 3ZKN 3ZKQ 3ZKS 3ZKX 3ZL7 3ZLQ 4BEL 4BFB 6JSZ 6UJ0 6UJ1 7D5B 7D5U 7F1G 7N4N
Enriched GO Terms of Interacting Partners?			Regulation Of Protein Folding
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