ARHGAP26 and PKN3

Number of citations of the paper that reports this interaction (PMID 11432776)
10

Data Source:
HPRD (in vivo, two hybrid)

		ARHGAP26	PKN3
Gene Name		Rho GTPase activating protein 26	protein kinase N3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytosol Cytoskeleton Focal Adhesion	Nucleus Golgi Apparatus Perinuclear Region Of Cytoplasm
	Molecular Function	Rho GTPase Activator Activity Protein Binding Phospholipid Binding	Protein Kinase Activity Protein Kinase C Activity Protein Binding ATP Binding
	Biological Process	Plasma Membrane Organization Small GTPase Mediated Signal Transduction Nervous System Development Actin Cytoskeleton Organization Positive Regulation Of Rho GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Protein Phosphorylation Signal Transduction Epithelial Cell Migration
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS			Eating disorders (purging via substances) ( 23568457) Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: CDC42 CDC42EP2 INSR PKN1 PKN3 PTK2 RHOA SRPK1	3 interactors: ARHGAP10 ARHGAP26 PLD1
Entrez ID		23092	29941
HPRD ID		05643	17856
Ensembl ID		ENSG00000145819	ENSG00000160447
Uniprot IDs		Q9UNA1	Q6P5Z2
PDB IDs		1UGV
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Intracellular Signal Transduction Cell Migration Epithelial Cell Migration Epithelium Migration Ephrin Receptor Signaling Pathway Cell Motility Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Organelle Organization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Cell Division Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Establishment Of Nucleus Localization Positive Regulation Of Kinase Activity Regulation Of Cytoskeleton Organization Locomotion Ameboidal-type Cell Migration Positive Regulation Of Transferase Activity Positive Regulation Of Signal Transduction Protein Phosphorylation Regulation Of Cell Motility Positive Regulation Of Phosphatidylinositol 3-kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Locomotion Positive Regulation Of Cell Cycle Process Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Movement Positive Regulation Of Protein Phosphorylation Positive Regulation Of Catalytic Activity Regulation Of Protein Kinase Activity Regulation Of Signal Transduction Nucleus Localization Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Cell Division Substantia Nigra Development Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Cytokinesis Regulation Of Kinase Activity Positive Regulation Of Cell Projection Organization Positive Regulation Of Cell Cycle Positive Regulation Of Phosphorylation Regulation Of Signaling Positive Regulation Of Cellular Component Biogenesis Organelle Organization Regulation Of Phosphatidylinositol 3-kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Phosphorylation Intracellular Signal Transduction	Small GTPase Mediated Signal Transduction Maintenance Of Golgi Location Positive Regulation Of Rho GTPase Activity Regulation Of Rho GTPase Activity Intracellular Signal Transduction Regulation Of Rho Protein Signal Transduction Regulation Of Microvillus Assembly Establishment Of Golgi Localization Positive Regulation Of Ras GTPase Activity Endomembrane System Organization Phosphatidylglycerol Biosynthetic Process Regulation Of Ras GTPase Activity Golgi Localization Regulation Of Ras Protein Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Positive Regulation Of Hydrolase Activity Cytoskeleton Organization Organelle Transport Along Microtubule Defense Response To Gram-positive Bacterium Golgi Organization Signal Transduction Positive Regulation Of Catalytic Activity Signaling
Tagcloud ?		ampar amphiphysin aqp4 biochip caspr2 comparably cv2 dner dppx gabar gad65 gad67 glra1b grm1 grm5 if1 lgl1 ma2 mog mosaics neuropsychiatrically nmdar1 questioning recoverin seroprevalence unambiguous upfront yo zic4
Tagcloud (Difference) ?		ampar amphiphysin aqp4 biochip caspr2 comparably cv2 dner dppx gabar gad65 gad67 glra1b grm1 grm5 if1 lgl1 ma2 mog mosaics neuropsychiatrically nmdar1 questioning recoverin seroprevalence unambiguous upfront yo zic4
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