CAND2 and CNOT3

Number of citations of the paper that reports this interaction (PMID 12207886)
1

Data Source:
HPRD (two hybrid, in vitro)

		CAND2	CNOT3
Gene Name		cullin-associated and neddylation-dissociated 2 (putative)	CCR4-NOT transcription complex, subunit 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus	Cytoplasmic MRNA Processing Body Nucleus Cytosol CCR4-NOT Complex
	Molecular Function	Protein Binding TBP-class Protein Binding	Protein Binding
	Biological Process	Transcription, DNA-templated SCF Complex Assembly Protein Ubiquitination Positive Regulation Of Transcription, DNA-templated	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Trophectodermal Cell Differentiation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Translation Gene Expression Gene Silencing By RNA Regulation Of Stem Cell Maintenance
Pathways			Deadenylation of mRNA Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CNOT3 GLP1R TBP UBE3C	7 interactors: CAND1 CAND2 CNOT1 CNOT2 CNOT8 CREBBP ID3
Entrez ID		23066	4849
HPRD ID		19120	05368
Ensembl ID		ENSG00000144712	ENSG00000088038
Uniprot IDs		O75155	O75175
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Silencing	Nuclear-transcribed MRNA Poly(A) Tail Shortening RNA Phosphodiester Bond Hydrolysis, Exonucleolytic SCF Complex Assembly Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Gene Silencing By RNA MRNA 3'-end Processing Regulation Of Cytoplasmic MRNA Processing Body Assembly Gene Silencing RNA 3'-end Processing RNA Phosphodiester Bond Hydrolysis Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process Regulation Of RNA Metabolic Process MRNA Catabolic Process Negative Regulation Of Gene Expression Regulation Of Stem Cell Maintenance Positive Regulation Of MRNA Catabolic Process RNA Catabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Organelle Assembly Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Gene Silencing By MiRNA Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Translation Posttranscriptional Gene Silencing Gene Expression Positive Regulation Of Cellular Component Biogenesis Cellular Macromolecule Biosynthetic Process Nucleic Acid Phosphodiester Bond Hydrolysis Macromolecule Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process MRNA Processing Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process
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