RBM34 and KIF23

Number of citations of the paper that reports this interaction (PubMedID 30217970)
38

Data Source:
BioGRID (two hybrid)

		RBM34	KIF23
Description		RNA binding motif protein 34	kinesin family member 23
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus	Nucleus Nucleoplasm Cytoplasm Mitochondrion Centrosome Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Focal Adhesion Midbody Mitotic Spindle Flemming Body Centralspindlin Complex
	Molecular Function	Nucleic Acid Binding RNA Binding	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity
	Biological Process	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA)	Mitotic Spindle Elongation Mitotic Cytokinesis Microtubule-based Movement Positive Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Cell Division
Pathways			MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Mitotic Telophase/Cytokinesis Kinesins
Drugs
Diseases
GWAS		Asthma ( 29273806) Night sleep phenotypes ( 27126917)	Mean reticulocyte volume ( 32888494) Rheumatoid arthritis (ACPA-positive) ( 24532676)
Interacting Genes		3 interacting genes: APP IKBKG KIF23	12 interacting genes: ACTA1 ARF3 CLK1 LATS2 PLK1 PPP1CB RACGAP1 RBM34 SUMO2 USP8 YWHAB YWHAG
Entrez ID		23029	9493
HPRD ID		11065	05455
Ensembl ID		ENSG00000188739	ENSG00000137807
Uniprot IDs		P42696	A0A7I2V5Y5 Q02241
PDB IDs			3VHX
Enriched GO Terms of Interacting Partners?		Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Mitotic Spindle Linear Polyubiquitin Binding Centralspindlin Complex Mitotic Spindle Elongation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Spindle Elongation Defense Response To Bacterium Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Cell Cycle Axon Choice Point Recognition Protein Heterodimerization Activity IkappaB Kinase Complex Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Regulation Of Proteolysis Cellular Response To Manganese Ion	Mitotic Cytokinesis Cytoskeleton-dependent Cytokinesis Regulation Of Protein Localization To Nucleus Spindle Midzone Midbody Cell Division Regulation Of Protein Localization Protein Sequestering Activity Neuromedin B Receptor Binding Protein Modification Process Myosin-light-chain-phosphatase Activity Negative Regulation Of Protein Localization To Nucleus Regulation Of Metabolic Process Extracellular Exosome Regulation Of Macromolecule Metabolic Process Protein Serine/threonine Kinase Activity Protein Serine Kinase Activity Sensory Perception Of Itch Sneeze Reflex Positive Regulation Of Testosterone Secretion Positive Regulation Of Osteoclast Proliferation Positive Regulation Of Respiratory Gaseous Exchange Leydig Cell Proliferation Positive Regulation Of Protein Metabolic Process Post-translational Protein Modification Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Synaptonemal Complex Disassembly Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Cytokinesis Regulation Of Protein Stability Intracellular Signal Transduction Golgi Inheritance Myosin Phosphatase Activity Negative Regulation Of Protein Phosphorylation Negative Regulation Of Kinase Activity Protein Kinase C Inhibitor Activity Negative Regulation Of Protein Kinase Activity Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Inner Cell Mass Cell Fate Commitment Inner Cell Mass Cellular Morphogenesis Centralspindlin Complex Actomyosin Contractile Ring Assembly
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