MLXIP and CNPY2

Number of citations of the paper that reports this interaction (PMID 12826659)
9

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		MLXIP	CNPY2
Gene Name		MLX interacting protein	canopy FGF signaling regulator 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrial Outer Membrane	Endoplasmic Reticulum Integral Component Of Plasma Membrane
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Dimerization Activity	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nucleocytoplasmic Transport Regulation Of Carbohydrate Metabolic Process By Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
Protein-Protein Interactions		3 interactors: CNPY2 MLX YWHAB	3 interactors: APP MLXIP MYLIP
Entrez ID		22877	10330
HPRD ID		10478	12056
Ensembl ID			ENSG00000257727
Uniprot IDs		Q9HAP2	Q9Y2B0
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Protein Dephosphorylation Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Receptor Biosynthetic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Metabolic Process Cytoplasmic Sequestering Of Protein Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Hippo Signaling Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Regulation Of Carbohydrate Metabolic Process By Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Low-density Lipoprotein Particle Clearance Axon Choice Point Recognition Posttranscriptional Regulation Of Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Protein Destabilization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Chemical Homeostasis Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
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