CNPY2 and MLXIP

Number of citations of the paper that reports this interaction (PMID 12826659)
9

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		CNPY2	MLXIP
Gene Name		canopy FGF signaling regulator 2	MLX interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Plasma Membrane	Nucleus Mitochondrial Outer Membrane
	Molecular Function	Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Dimerization Activity
	Biological Process	Negative Regulation Of Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nucleocytoplasmic Transport Regulation Of Carbohydrate Metabolic Process By Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
Protein-Protein Interactions		3 interactors: APP MLXIP MYLIP	3 interactors: CNPY2 MLX YWHAB
Entrez ID		10330	22877
HPRD ID		12056	10478
Ensembl ID		ENSG00000257727
Uniprot IDs		Q9Y2B0	Q9HAP2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Carbohydrate Metabolic Process By Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Low-density Lipoprotein Particle Clearance Axon Choice Point Recognition Posttranscriptional Regulation Of Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Protein Destabilization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Chemical Homeostasis Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway	Negative Regulation Of Gene Expression Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Protein Dephosphorylation Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Receptor Biosynthetic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Metabolic Process Cytoplasmic Sequestering Of Protein Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Hippo Signaling Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
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