OSCAR and FCAR

Number of citations of the paper that reports this interaction (PMID 15085135)
144

Data Source:
HPRD (in vitro)

		OSCAR	FCAR
Gene Name		osteoclast associated, immunoglobulin-like receptor	Fc fragment of IgA, receptor for
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function		IgA Binding
	Biological Process		Immune Response
Pathways
Drugs
Diseases
GWAS		Response to taxane treatment (docetaxel) ( 23006423)
Protein-Protein Interactions		1 interactors: FCAR	6 interactors: CD79A FCGR1A LYN OSCAR PILRA PPP2CA
Entrez ID		126014	2204
HPRD ID		06035	00914
Ensembl ID		ENSG00000170909	ENSG00000186431
Uniprot IDs		Q8IYS5	P24071
PDB IDs			1OVZ 1OW0 1UCT
Enriched GO Terms of Interacting Partners?			Immune Response-activating Cell Surface Receptor Signaling Pathway B Cell Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Negative Regulation Of MAP Kinase Activity Regulation Of JAK-STAT Cascade Positive Regulation Of Immune Response Positive Regulation Of Oligodendrocyte Progenitor Proliferation Negative Regulation Of Mast Cell Proliferation Negative Regulation Of Protein Serine/threonine Kinase Activity Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of MAPK Cascade Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Immune Response Positive Regulation Of Immune System Process Signal Transduction Tolerance Induction To Self Antigen Fc Receptor Mediated Inhibitory Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Regulation Of Peptidyl-tyrosine Phosphorylation Signaling Negative Regulation Of Protein Kinase Activity Cell Communication Negative Regulation Of Kinase Activity Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Immune Response-inhibiting Signal Transduction Phagocytosis Fc Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of MAP Kinase Activity Regulation Of Immune System Process Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Tolerance Induction Positive Regulation Of Mast Cell Proliferation Negative Regulation Of Transferase Activity Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Protein Phosphorylation Cellular Response To Stimulus Leukocyte Differentiation Regulation Of Oligodendrocyte Progenitor Proliferation Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Mitotic Nuclear Envelope Reassembly Protein Heterotrimerization Histamine Secretion By Mast Cell Nuclear Envelope Reassembly
Tagcloud ?		angelica arthritis attention bmms bone collectively complication cytotoxicity destructive erosion extract fos jnk jun macrophages marrow nfatc1 osteoclast osteolysis p65 periodontal periprosthetic precursor preventative rankl rheumatoid sequentially serve sinensis	anca antineutrophil assembled cd11b confocal degranulation engagement extracellcular fcgr3b fcr fcrs genetics granulomatosis haplotype iga igg illumina mucosal multicenter na1 na2 neutrophil polyangiitis pyrosequencing tagging taqman unappreciated vasculitis wegener
Tagcloud (Difference) ?		angelica arthritis attention bmms bone collectively complication cytotoxicity destructive erosion extract fos jnk jun macrophages marrow nfatc1 osteoclast osteolysis p65 periodontal periprosthetic precursor preventative rankl rheumatoid sequentially serve sinensis	anca antineutrophil assembled cd11b confocal degranulation engagement extracellcular fcgr3b fcr fcrs genetics granulomatosis haplotype iga igg illumina mucosal multicenter na1 na2 neutrophil polyangiitis pyrosequencing tagging taqman unappreciated vasculitis wegener
Tagcloud (Intersection) ?