FAT1 and IGLL1

Number of citations of the paper that reports this interaction (PubMedID 28129444)
0

Data Source:
BioGRID (two hybrid)

		FAT1	IGLL1
Description		FAT atypical cadherin 1	immunoglobulin lambda like polypeptide 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Focal Adhesion Membrane Apical Plasma Membrane Lamellipodium Cell Junction Filopodium Perinuclear Region Of Cytoplasm Extracellular Exosome	Extracellular Region Endoplasmic Reticulum Membrane IgG Immunoglobulin Complex
	Molecular Function	Calcium Ion Binding Protein Binding	Antigen Binding Protein Binding
	Biological Process	Lens Development In Camera-type Eye Epithelial Cell Morphogenesis Establishment Of Epithelial Cell Apical/basal Polarity Involved In Camera-type Eye Morphogenesis Actin Filament Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Establishment Or Maintenance Of Cell Polarity Cell-cell Signaling Anatomical Structure Morphogenesis Cell Migration Camera-type Eye Development Cell-cell Adhesion Mediated By Cadherin Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Camera-type Eye Morphogenesis Cell-cell Adhesion Cellular Response To Angiotensin Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration	Immune Response Immunoglobulin Mediated Immune Response
Pathways			Cell surface interactions at the vascular wall
Drugs			Copper
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Alzheimer disease and age of onset ( 26830138) Carotid plaque burden ( 28282560) Chronotype ( 26955885) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Macular thickness ( 30535121) Major depressive disorder ( 29317602) Medication use (calcium channel blockers) ( 31015401) Mild obesity-related type 2 diabetes ( 34737425) Morning vs. evening chronotype ( 26955885) Obesity ( 21552555) PR interval ( 30046033 32439900) Triglyceride levels in HIV infection ( 33109212) Urinary albumin-to-creatinine ratio ( 31630189)	Blood protein levels ( 30072576) Height ( 18391951) HOMA-B (corrected for HOMA-IR) ( 30369944) Migraine ( 21448238) Peripheral artery disease ( 25009551)
Interacting Genes		12 interacting genes: CLK1 ENAH HOMER1 HOMER3 IGLL1 MT-ND1 NOXA1 SORBS2 TRAF4 TRIM14 UBC VASP	6 interacting genes: FAM25A FAM25C FAM25G FAT1 MYOC UBQLN2
Entrez ID		2195	3543
HPRD ID		02986	00905
Ensembl ID		ENSG00000083857	ENSG00000128322
Uniprot IDs		Q14517	P15814
PDB IDs			2H32 2H3N 2LKQ
Enriched GO Terms of Interacting Partners?		G Protein-coupled Glutamate Receptor Binding Profilin Binding SH3 Domain Binding G Protein-coupled Glutamate Receptor Signaling Pathway Regulation Of Store-operated Calcium Entry Anchoring Junction WW Domain Binding Dendrite Lamellipodium Postsynapse Glutamate Receptor Signaling Pathway Actin Polymerization Or Depolymerization Regulation Of Synaptic Transmission, Glutamatergic Filopodium Signaling Adaptor Activity Protein Tetramerization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?