PLAC9 and CCDC14

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		PLAC9	CCDC14
Description		placenta associated 9	coiled-coil domain containing 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Cytoplasm Centrosome Cytoskeleton Cilium Microtubule Cytoskeleton Centriolar Satellite Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Substantia Nigra Development Protein Localization To Centrosome
Pathways
Drugs
Diseases
GWAS		Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)	Intelligence (MTAG) ( 29326435)
Interacting Genes		6 interacting genes: CCDC14 EMILIN1 GPRASP2 RAPGEF5 RNF213 SNAPIN	17 interacting genes: APP CALM1 CEP63 CSNK1D CSNK1E DDX6 KDM1A MAGEA11 MAGEB4 MAPK14 PEX5 PIK3R3 PLAC9 PNKP RNF8 TXLNB UBQLN4
Entrez ID		219348	64770
HPRD ID		18491	07801
Ensembl ID		ENSG00000189129	ENSG00000175455
Uniprot IDs		Q5JTB5 Q5JTB6	J3QT39 Q49A88
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Late Endosome To Lysosome Transport Lipid Ubiquitination	Regulation Of Double-strand Break Repair Regulation Of Canonical Wnt Signaling Pathway Response To Radiation DNA Damage Response Positive Regulation Of Non-canonical Wnt Signaling Pathway Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of DNA Repair Regulation Of Cellular Response To Stress Regulation Of Wnt Signaling Pathway Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Proteolysis Neuron Maturation Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Amyloid Precursor Protein Catabolic Process Spindle Pole Cellular Response To Stress Response To Ionizing Radiation Signal Transduction In Response To DNA Damage Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Non-canonical Wnt Signaling Pathway Regulation Of DNA Recombination DNA Repair-dependent Chromatin Remodeling Negative Regulation Of Metabolic Process Enzyme Binding Regulation Of Metabolic Process Negative Regulation Of Wnt Signaling Pathway Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein-containing Complex Positive Regulation Of Proteolysis Amyloid-beta Complex Growth Cone Lamellipodium Protein Metabolic Process Regulation Of Response To Calcium Ion Response To Nerve Growth Factor Amylin Binding Positive Regulation Of Toll Signaling Pathway Endocytosis Cytosol Cellular Response To Nerve Growth Factor Stimulus Spindle Microtubule Regulation Of Proteasomal Protein Catabolic Process Concave Side Of Sperm Head Positive Regulation Of Protein Catabolic Process Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of DNA Metabolic Process Cellular Response To CAMP
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