FABP2 and ALDH1B1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		FABP2	ALDH1B1
Description		fatty acid binding protein 2	aldehyde dehydrogenase 1 family member B1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Microvillus Apical Cortex	Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Long-chain Fatty Acid Transmembrane Transporter Activity Fatty Acid Binding Protein Binding Lipid Binding Long-chain Fatty Acid Binding	Aldehyde Dehydrogenase (NAD+) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor NAD Binding
	Biological Process	Fatty Acid Metabolic Process Fatty Acid Transport Long-chain Fatty Acid Transport Intestinal Absorption Intestinal Lipid Absorption	Carbohydrate Metabolic Process Ethanol Catabolic Process Aldehyde Metabolic Process
Pathways		Triglyceride catabolism	Ethanol oxidation Mitochondrial protein degradation
Drugs		Ibuprofen Dexibuprofen	NADH
Diseases
GWAS		Refractive error ( 32231278)	Alcohol consumption (drinkers vs non-drinkers) ( 31959922) Clostridioides difficle infection in antibiotics-users ( 33841421) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Longevity (100 years and older) ( 33948810) Metabolite levels ( 23823483) Pulse pressure ( 27841878) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 27841878) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		4 interacting genes: AGR2 ALDH1B1 CFTR TERF2IP	5 interacting genes: EXOSC10 FABP2 FILNC1 OGT XRN2
Entrez ID		2169	219
HPRD ID		00611	00005
Ensembl ID		ENSG00000145384	ENSG00000137124
Uniprot IDs		P12104	A0A384MTJ7 P30837
PDB IDs		1KZW 1KZX 2MJI 2MO5 3AKM 3IFB 6L7K	7MJC 7MJD 7RAD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Lung Goblet Cell Differentiation Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of Enamel Mineralization Positive Regulation Of PERK-mediated Unfolded Protein Response Alcohol Metabolic Process Response To Endoplasmic Reticulum Stress Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Regulation Of Body Fluid Levels Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Protection From Non-homologous End Joining At Telomere Shelterin Complex Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of IRE1-mediated Unfolded Protein Response Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Dystroglycan Binding Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Ethanol Metabolic Process Aldehyde Dehydrogenase (NAD+) Activity Ethanol Catabolic Process Regulation Of Monoatomic Anion Transport Cellular Response To Stress Epithelial Fluid Transport Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Protein Localization To Chromosome, Telomeric Region Telomere Capping Golgi-associated Vesicle Membrane Telomere Maintenance In Response To DNA Damage Cellular Response To Forskolin Mucus Secretion Regulation Of IRE1-mediated Unfolded Protein Response Regulation Of PERK-mediated Unfolded Protein Response Positive Regulation Of Protein Localization Response To Forskolin Positive Regulation Of Cell Communication Positive Regulation Of Signaling Chloride Transmembrane Transporter Activity Sperm Capacitation Oxidoreductase Activity, Acting On The Aldehyde Or Oxo Group Of Donors, NAD Or NADP As Acceptor	Cellular Response To Nutrient 3'-5'-RNA Exonuclease Activity Lipid Binding Exonuclease Activity Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Nuclear Polyadenylation-dependent SnoRNA Catabolic Process Nuclear Polyadenylation-dependent SnRNA Catabolic Process Nuclear Polyadenylation-dependent CUT Catabolic Process Nuclease Activity Nuclear-transcribed MRNA Catabolic Process Transcription Termination Site Sequence-specific DNA Binding MRNA Catabolic Process Apical Cortex Long-chain Fatty Acid Binding Response To Nutrient Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRNA Surveillance RNA Catabolic Process SnRNA Catabolic Process TRAMP-dependent TRNA Surveillance Pathway RRNA Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process Sno(s)RNA Catabolic Process Positive Regulation Of MRNA Cis Splicing, Via Spliceosome CUT Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Termination Of RNA Polymerase II Transcription 5'-3' RNA Exonuclease Activity Poly(A)-dependent SnoRNA 3'-end Processing RRNA Metabolic Process Positive Regulation Of Monocyte Differentiation Cellular Response To Nutrient Levels RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) Regulation Of Transcription By Glucose 5'-3' Exonuclease Activity Cellular Response To Vitamin D TRNA Decay Nuclear MRNA Surveillance NSL Complex Myoblast Proliferation Regulation Of Telomerase RNA Localization To Cajal Body Intestinal Lipid Absorption
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