EVI2A and RNF114

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EVI2A	RNF114
Gene Name		ecotropic viral integration site 2A	ring finger protein 114
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Intracellular Nucleus Cytoplasm
	Molecular Function	Transmembrane Signaling Receptor Activity	Zinc Ion Binding Ligase Activity
	Biological Process	Signal Transduction	Multicellular Organismal Development Spermatogenesis Protein Ubiquitination Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Psoriasis ( 20953189)
Protein-Protein Interactions		3 interactors: APP RNF114 RORC	26 interactors: AK5 BMI1 EVI2A MAPK3 RNF38 RPSA TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2U UBE2W UEVLD XAF1
Entrez ID		2123	55905
HPRD ID		08866	10329
Ensembl ID			ENSG00000124226
Uniprot IDs		P22794	Q9Y508
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis T-helper 17 Cell Differentiation Axon Choice Point Recognition Negative Regulation Of Thymocyte Apoptotic Process Neuron Remodeling Regulation Of Gamma-delta T Cell Differentiation Lymph Node Development Peyer's Patch Development Cellular Response To Sterol Regulation Of Thymocyte Apoptotic Process Cellular Copper Ion Homeostasis Positive Regulation Of Circadian Rhythm Cell Activation Cellular Protein Modification Process Copper Ion Homeostasis Suckling Behavior Regulation Of Transcription Involved In Cell Fate Commitment Cell Differentiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Sexual Reproduction Negative Regulation Of T Cell Apoptotic Process T-helper Cell Differentiation Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Adipose Tissue Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway CD4-positive, Alpha-beta T Cell Differentiation CD4-positive, Alpha-beta T Cell Activation Reproduction Ionotropic Glutamate Receptor Signaling Pathway Regulation Of T Cell Apoptotic Process Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Cellular Protein Metabolic Process Axon Cargo Transport Mating Neuromuscular Junction Development Negative Regulation Of Leukocyte Apoptotic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process	Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Protein Modification Process Cellular Protein Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Toll-like Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Metabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein Catabolic Process Activation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Innate Immune Response Protein K63-linked Ubiquitination Regulation Of Innate Immune Response Positive Regulation Of Protein Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Ligase Activity Cellular Response To Stress Proteolysis Regulation Of Protein Ubiquitination Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Apoptotic Process Cellular Response To Oxygen Levels Programmed Cell Death Histone Ubiquitination Catabolic Process Immune Response-regulating Signaling Pathway Cell Death Death Protein Monoubiquitination Innate Immune Response
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