NR2F6 and ANGPTL1

Number of citations of the paper that reports this interaction (PMID 10318855)
8

Data Source:
HPRD (in vitro, in vivo)

		NR2F6	ANGPTL1
Gene Name		nuclear receptor subfamily 2, group F, member 6	angiopoietin-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Thyroid Hormone Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding	Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Gene Expression Intracellular Receptor Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Steroid Hormone Mediated Signaling Pathway Neuron Development Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Pathways		Generic Transcription Pathway Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ANGPTL1 BCL11A CBX1 ESR1 NAP1L1 NCOA1 NR2F2 NR3C1 NSD1 RARG RXRA THRB	2 interactors: NR2F6 TEK
Entrez ID		2063	9068
HPRD ID		00583	04851
Ensembl ID		ENSG00000160113	ENSG00000116194
Uniprot IDs		B4DQE4 F1D8R3 P10588	O95841
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Response To Steroid Hormone Positive Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Hormone Stimulus Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Organic Cyclic Compound Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Lipid Negative Regulation Of Gene Expression Response To Lipid DNA-templated Transcription, Initiation Response To Organic Cyclic Compound Response To Hormone Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Reproductive Process Negative Regulation Of Biosynthetic Process Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Gland Development Reproductive Structure Development Reproductive System Development Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Anatomical Structure Morphogenesis Epithelial Cell Differentiation Gene Expression Prostate Gland Development Reproduction Heterocycle Metabolic Process	Response To Steroid Hormone Tie Signaling Pathway Positive Regulation Of Cytokine Secretion Involved In Immune Response Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of Actin Cytoskeleton Reorganization Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Response To Lipid Heart Trabecula Formation Response To Organic Cyclic Compound Endothelial Cell Proliferation Response To Hormone Entrainment Of Circadian Clock By Photoperiod Definitive Hemopoiesis Negative Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Focal Adhesion Assembly Photoperiodism Entrainment Of Circadian Clock Positive Regulation Of Adherens Junction Organization Response To Abiotic Stimulus Detection Of Temperature Stimulus Heart Trabecula Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase Activity Sensory Perception Of Temperature Stimulus Regulation Of Vascular Permeability Regulation Of Endothelial Cell Apoptotic Process Regulation Of Actin Cytoskeleton Reorganization Regulation Of Establishment Or Maintenance Of Cell Polarity Regulation Of NIK/NF-kappaB Signaling Endochondral Ossification Substrate Adhesion-dependent Cell Spreading Regulation Of Focal Adhesion Assembly Trabecula Morphogenesis Positive Regulation Of Cytokine Production Involved In Immune Response Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Cell-matrix Adhesion Sprouting Angiogenesis Positive Regulation Of Endothelial Cell Migration Regulation Of Lipid Kinase Activity Regulation Of Cell Junction Assembly Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Cell Development Regulation Of Cytokine Production Involved In Immune Response Organ Regeneration Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Epithelial Cell Migration Negative Regulation Of Angiogenesis Endochondral Bone Morphogenesis Regulation Of Endothelial Cell Proliferation
Tagcloud ?		another arp as4 augmented chip circ coup divergent ear2 effected enhancer exert hre huang initiating knocked liu luciferase negatively nr2f2 potently queues renin res screen sigmund surprisingly tfii twofold	achieving anovulatory blastocyst ccs competence competent cumulus embryo folliculogenesis grin2a infertility ivf lhcgr melanogenesis microarrays microenvironment oocyte ovary paracrine pcos polycystic qrt sfrp4 signatures socs3 talk tnik transendothelial u133
Tagcloud (Difference) ?		another arp as4 augmented chip circ coup divergent ear2 effected enhancer exert hre huang initiating knocked liu luciferase negatively nr2f2 potently queues renin res screen sigmund surprisingly tfii twofold	achieving anovulatory blastocyst ccs competence competent cumulus embryo folliculogenesis grin2a infertility ivf lhcgr melanogenesis microarrays microenvironment oocyte ovary paracrine pcos polycystic qrt sfrp4 signatures socs3 talk tnik transendothelial u133
Tagcloud (Intersection) ?