NR2F6 and ANGPTL1

Number of citations of the paper that reports this interaction (PubMedID 10318855)
50

Data Source:
HPRD (in vitro, in vivo)

		NR2F6	ANGPTL1
Description		nuclear receptor subfamily 2 group F member 6	angiopoietin like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Mitochondrion	Extracellular Region Extracellular Space Extracellular Matrix Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Signaling Receptor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Nervous System Development Cell Differentiation Intracellular Receptor Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Neuron Development Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Blood Coagulation
Pathways		Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Mitochondrial DNA copy number ( 30704525) Night sleep phenotypes ( 27126917)	Blood protein levels ( 30072576) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		12 interacting genes: ANGPTL1 BCL11A CBX1 ESR1 NAP1L1 NCOA1 NR2F2 NR3C1 NSD1 RARG RXRA THRB	2 interacting genes: NR2F6 TEK
Entrez ID		2063	9068
HPRD ID		00583	04851
Ensembl ID		ENSG00000160113	ENSG00000116194
Uniprot IDs		F1D8R3 P10588	O95841
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Receptor Activity Nuclear Receptor-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Hormone-mediated Signaling Pathway Chromatin Regulation Of Thyroid Hormone Receptor Signaling Pathway Chromatin Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Nuclear Retinoid X Receptor Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Sequence-specific DNA Binding Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process Reproductive Behavior Sequence-specific Double-stranded DNA Binding RNA Polymerase II Transcription Regulator Complex Nuclear Estrogen Receptor Binding Cellular Response To Hormone Stimulus Negative Regulation Of Macromolecule Biosynthetic Process Nucleoplasm Negative Regulation Of Biosynthetic Process MRNA Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Reproductive Structure Development MRNA Transcription Response To Lipid Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Female Receptivity Female Mating Behavior Regulation Of RNA Metabolic Process Chromatin Organization Zinc Ion Binding Positive Regulation Of Biosynthetic Process Transcription Regulator Complex Negative Regulation Of Metabolic Process	Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Cell Development Photoperiodism Entrainment Of Circadian Clock Detection Of Temperature Stimulus Involved In Sensory Perception Entrainment Of Circadian Clock By Photoperiod Detection Of Temperature Stimulus System Development Definitive Hemopoiesis Sprouting Angiogenesis Positive Regulation Of Rac Protein Signal Transduction Glomerulus Vasculature Development Negative Regulation Of Endothelial Cell Apoptotic Process Heart Trabecula Formation Endothelial Cell Proliferation Regulation Of Establishment Or Maintenance Of Cell Polarity Regulation Of Rac Protein Signal Transduction Positive Regulation Of Focal Adhesion Assembly Tie Signaling Pathway Positive Regulation Of Rho Protein Signal Transduction Regulation Of Vascular Permeability Substrate Adhesion-dependent Cell Spreading Nuclear Receptor Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of Endothelial Cell Apoptotic Process Regulation Of Cell-substrate Junction Organization Positive Regulation Of Cell-matrix Adhesion Regulation Of Focal Adhesion Assembly Basal Plasma Membrane Cellular Response To Mechanical Stimulus Vasculature Development Microvillus Positive Regulation Of Small GTPase Mediated Signal Transduction
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