HACD2 and BCAP31

Number of citations of the paper that reports this interaction (PMID 15024066)
7

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (two hybrid, in vitro)

		HACD2	BCAP31
Gene Name		3-hydroxyacyl-CoA dehydratase 2	B-cell receptor-associated protein 31
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Particle Cytosol Integral Component Of Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding 3-hydroxyacyl-CoA Dehydratase Activity Enzyme Binding	Protein Binding Protein Complex Binding MHC Class I Protein Binding
	Biological Process	Sphingolipid Biosynthetic Process Fatty Acid Elongation Very Long-chain Fatty Acid Biosynthetic Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Cytosolic Calcium Ion Concentration Spermatogenesis Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase Class I MHC mediated antigen processing & presentation Antigen Presentation: Folding, assembly and peptide loading of class I MHC Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: BCAP31 TECR	25 interactors: ACTG1 APP BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 LMAN1 MSN MYH10 PLP2 SERPINF2 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ
Entrez ID		201562	10134
HPRD ID		17930	02319
Ensembl ID			ENSG00000185825
Uniprot IDs		Q6Y1H2	P51572
PDB IDs			4JZL 4JZP
Enriched GO Terms of Interacting Partners?		Protein Localization To Endoplasmic Reticulum Exit Site Very Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Calcium-mediated Signaling Using Intracellular Calcium Source Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Mitochondrial Calcium Ion Homeostasis Fatty-acyl-CoA Biosynthetic Process Long-chain Fatty-acyl-CoA Metabolic Process Very Long-chain Fatty Acid Metabolic Process Endoplasmic Reticulum Calcium Ion Homeostasis Triglyceride Biosynthetic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Acyl-CoA Metabolic Process Execution Phase Of Apoptosis Calcium-mediated Signaling Triglyceride Metabolic Process ER To Golgi Vesicle-mediated Transport Neutral Lipid Metabolic Process	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Establishment Of Localization In Cell Release Of Cytochrome C From Mitochondria Regulation Of Mitochondrion Organization Vesicle-mediated Transport Membrane Organization Cellular Localization Apoptotic Process Response To Wounding Neuron Apoptotic Process Immune System Process Programmed Cell Death Positive Regulation Of Peptidase Activity Positive Regulation Of Mitochondrion Organization Cell Death Death Neuron Death Secretion By Cell Apoptotic Mitochondrial Changes Exocytosis Apoptotic Signaling Pathway Organelle Fusion Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Transport Positive Regulation Of Cell Death Regulation Of Endopeptidase Activity Secretion Immune Response Positive Regulation Of Organelle Organization Regulation Of Peptidase Activity Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Transport Regulation Of Cellular Localization Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Cysteine-type Endopeptidase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Membrane Fusion Intracellular Transport Regulation Of Protein Localization Positive Regulation Of Endopeptidase Activity
Tagcloud ?			24h 48h anova aureus caprine cd2bp2 challenged chemotactic cxcl6 dairy fosl2 goats granulocyte halves ilt5 infused intramammary intricacy junb lymphotoxin mapk13 mastitis mhcii microarrays mscs pbs udder udders veterinary
Tagcloud (Difference) ?			24h 48h anova aureus caprine cd2bp2 challenged chemotactic cxcl6 dairy fosl2 goats granulocyte halves ilt5 infused intramammary intricacy junb lymphotoxin mapk13 mastitis mhcii microarrays mscs pbs udder udders veterinary
Tagcloud (Intersection) ?