HACD2 and BCAP31

Number of citations of the paper that reports this interaction (PubMedID 15024066)
58

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, two hybrid)

		HACD2	BCAP31
Description		3-hydroxyacyl-CoA dehydratase 2	B cell receptor associated protein 31
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Perinuclear Endoplasmic Reticulum Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Lyase Activity 3-hydroxyacyl-CoA Dehydratase Activity Enzyme Binding Very-long-chain (3R)-3-hydroxyacyl-CoA Dehydratase Activity	Protein Binding MHC Class I Protein Binding Protein-containing Complex Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Sphingolipid Biosynthetic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Protein Targeting To Mitochondrion Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Spermatogenesis Protein Transport Vesicle-mediated Transport Response To Endoplasmic Reticulum Stress Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Positive Regulation Of ERAD Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Synthesis of very long-chain fatty acyl-CoAs	Apoptotic cleavage of cellular proteins Apoptotic execution phase RHOA GTPase cycle Antigen Presentation: Folding, assembly and peptide loading of class I MHC RSV-host interactions
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031)
Interacting Genes		6 interacting genes: BCAP31 CREB3L1 FAM209A SMIM1 TMX2 UBC	30 interacting genes: ACTG1 APP AQP2 BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 CDC42 CEBPA DRD2 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 MSN MYH10 PLP2 SERPINF2 TIMMDC1 TMEM31 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ
Entrez ID		201562	10134
HPRD ID		17930	02319
Ensembl ID		ENSG00000206527	ENSG00000185825
Uniprot IDs		Q6Y1H2	P51572
PDB IDs			4JZL 4JZP 8XWX
Enriched GO Terms of Interacting Partners?		Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Endoplasmic Reticulum Membrane Regulation Of Response To Endoplasmic Reticulum Stress	Response To Peptide Response To Cytokine Regulation Of Transport SNARE Complex Assembly Response To Metal Ion Cell Projection Morphogenesis Positive Regulation Of Gene Expression Axonogenesis Neuron Projection Morphogenesis Cellular Response To Type II Interferon Membrane Positive Regulation Of Interleukin-1 Production Regulation Of Defense Response Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Regulation Of Inflammatory Response Regulation Of Body Fluid Levels Dendritic Cell Apoptotic Process Positive Regulation Of Inflammatory Response Membrane Organization Cellular Component Assembly Vesicle-mediated Transport Neuron Projection Positive Regulation Of Cytokine Production Response To Type II Interferon Mitochondrial Outer Membrane Regulation Of Vesicle-mediated Transport Protein-containing Complex SNAP Receptor Activity Regulation Of Immune System Process BH3 Domain Binding Response To Anesthetic Channel Activity Regulation Of Interleukin-1 Production Renal System Process Blood Microparticle Regulation Of Cytokine Production Response To Nicotine Pyroptotic Inflammatory Response Death-inducing Signaling Complex Regulation Of Histamine Secretion By Mast Cell Defense Response Cell Surface Receptor Signaling Pathway Macrophage Differentiation SNARE Complex Epithelial Cell Apoptotic Process Leukocyte Apoptotic Process Synaptic Vesicle Membrane Endocytosis Negative Regulation Of Dendritic Cell Apoptotic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?