SLC16A13 and HSD3B1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		SLC16A13	HSD3B1
Name		solute carrier family 16 member 13	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane	Nucleolus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cilium Microtubule Cytoskeleton Membrane Smooth Endoplasmic Reticulum Membrane Mitochondrial Membrane Intracellular Membrane-bounded Organelle Intercellular Bridge
	Molecular Function	Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity Catalytic Activity 3-beta-hydroxy-Delta5-steroid Dehydrogenase (NAD+) Activity Steroid Delta-isomerase Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Isomerase Activity 5-alpha-androstane-3-beta,17-beta-diol Dehydrogenase (NADP+) Activity
	Biological Process	Monocarboxylic Acid Transport Transmembrane Transport	Lipid Metabolic Process Steroid Biosynthetic Process Progesterone Biosynthetic Process Androgen Biosynthetic Process Estrogen Biosynthetic Process Steroid Metabolic Process C21-steroid Hormone Metabolic Process
Pathways		None	Androgen biosynthesis Mineralocorticoid biosynthesis Glucocorticoid biosynthesis
Drugs		None	NADH Trilostane Androstenedione Hydrocortisone aceponate Hydrocortisone acetate Hydrocortisone butyrate Hydrocortisone cypionate Hydrocortisone phosphate Hydrocortisone probutate Hydrocortisone valerate
GWAS		Type 2 diabetes ( 23945395 24390345 26818947 )	Diisocyanate-induced asthma ( 25918132 )
Interacting Genes		19 interacting genes: AQP6 ATP13A1 BSG CCNDBP1 CD79A CREB3L1 FAM210B FXYD6-FXYD2 GJA8 HSD3B1 JPH1 PGRMC2 PTPN9 SHISAL1 SLC10A1 SYNDIG1 TMEM14B TMEM160 TMEM50B	3 interacting genes: AQP6 SLC16A13 TMEM14B
Entrez ID		201232	3283
HPRD ID		18054	04920
Ensembl ID		ENSG00000174327	ENSG00000203857
Uniprot IDs		Q7RTY0	P14060
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Monoatomic Anion Channel Activity Ammonium Transmembrane Transport Ammonium Channel Activity Renal Water Transport Water Channel Activity Carbon Dioxide Transport Monocarboxylic Acid Transmembrane Transporter Activity One-carbon Compound Transport Water Transport Tetrapyrrole Biosynthetic Process Porphyrin-containing Compound Biosynthetic Process Heme Biosynthetic Process Fluid Transport Heme Metabolic Process Channel Activity Porphyrin-containing Compound Metabolic Process Tetrapyrrole Metabolic Process Pigment Metabolic Process Transmembrane Transport Cerebral Cortex Development Chloride Transmembrane Transport Odontogenesis Neural Precursor Cell Proliferation Symporter Activity Chloride Transport