SOX14 and NAIF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SOX14	NAIF1
Description		SRY-box transcription factor 14	nuclear apoptosis inducing factor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Nucleus Nucleoplasm Mitochondrion Cytosol Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Nervous System Development Brain Development Visual Perception Entrainment Of Circadian Clock Neuron Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neuron Migration	Apoptotic Process Negative Regulation Of Cell Growth Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Glucocorticoid-induced osteonecrosis ( 26265699)	Albumin-globulin ratio ( 29403010) Body mass index ( 26426971) Monocyte count ( 29403010)
Interacting Genes		9 interacting genes: CRX FOXH1 KRTAP15-1 NAIF1 ROR2 SPMIP9 TRIM54 VENTX ZDHHC17	5 interacting genes: CCNDBP1 PAX4 SOX14 TERF2 TERF2IP
Entrez ID		8403	203245
HPRD ID		16067	12987
Ensembl ID		ENSG00000168875	ENSG00000171169
Uniprot IDs		O95416	Q69YI7
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of DNA Recombination At Telomere Shelterin Complex Protection From Non-homologous End Joining At Telomere Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region Telomere Capping Telomere Maintenance In Response To DNA Damage RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Negative Regulation Of DNA Recombination Male Germ Cell Nucleus Nuclear Body Positive Regulation Of Telomere Maintenance Telomere Cap Complex DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Recombination Negative Regulation Of Chromosome Organization Axonal Transport Of Messenger Ribonucleoprotein Complex Negative Regulation Of Telomere Single Strand Break Repair Telomere Maintenance Positive Regulation Of Chromosome Organization Protein Localization To Chromosome Regulation Of Telomere Maintenance Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Telomere Organization Negative Regulation Of DNA Metabolic Process Regulation Of DNA Recombination Negative Regulation Of T-circle Formation Chromosome, Telomeric Region Negative Regulation Of Mitotic Recombination Regulation Of DNA Repair Brain Development Telomerase Activity Regulation Of Mitotic Recombination Regulation Of Chromosome Organization Negative Regulation Of Telomere Capping Type B Pancreatic Cell Differentiation Positive Regulation Of DNA Metabolic Process Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Telomeric Loop Disassembly Chromosome Organization Regulation Of Telomere Capping Enteroendocrine Cell Differentiation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase
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