PRDM5 and RASD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRDM5	RASD1
Description		PR/SET domain 5	ras related dexamethasone induced 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Body	Nucleus Cytoplasm Plasma Membrane Membrane Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Sequence-specific DNA Binding Metal Ion Binding DNA-binding Transcription Factor Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding G-protein Beta-subunit Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Chromatin Organization Methylation Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Extracellular Matrix Organization Cellular Response To Leukemia Inhibitory Factor	Signal Transduction G Protein-coupled Receptor Signaling Pathway Nitric Oxide Mediated Signal Transduction Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		F-cell distribution in sickle cell anaemia ( 21326311) Fasting plasma glucose ( 17903298) Hemoglobin levels ( 33491795) Loneliness (multivariate analysis) ( 27629369) Monobrow thickness ( 26926045) Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Sensorimotor dexterity ( 31596458)	A body shape index ( 34021172) Chronotype ( 30696823) Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		7 interacting genes: ADPRS CLCN1 FAAP20 FBXO44 RASD1 TYK2 VIPR1	38 interacting genes: ABI2 BHLHE41 CCDC57 CDR2L CYSRT1 EXOSC8 GNAI1 GNAI2 GNB1 HNRNPK HNRNPR KHDRBS3 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP5-9 KRTAP6-2 KRTAP6-3 MATR3 MDFI MKRN3 MTUS2 NBPF19 NOS1 NOS1AP NOTCH2NLA PLSCR1 PRDM5 PTPN21 RASAL3 RBMY1A1 RBMY1F RBMY1J TRIM37 WWP2
Entrez ID		11107	51655
HPRD ID		17902	08958
Ensembl ID		ENSG00000138738	ENSG00000108551
Uniprot IDs		Q9NQX1	Q9Y272
PDB IDs		6XAZ
Enriched GO Terms of Interacting Partners?		ADP-ribosylserine Hydrolase Activity Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation Interleukin-12 Receptor Complex Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Poly(ADP-ribose) Glycohydrolase Activity Voltage-gated Chloride Channel Activity Interleukin-23-mediated Signaling Pathway Growth Hormone Receptor Binding Interleukin-10-mediated Signaling Pathway Receptor Complex Extrinsic Component Of Plasma Membrane Positive Regulation Of NK T Cell Proliferation Interleukin-12-mediated Signaling Pathway Interleukin-23 Receptor Complex Type III Interferon-mediated Signaling Pathway Positive Regulation Of NK T Cell Activation Response To Superoxide Response To Oxygen Radical Protein De-ADP-ribosylation O-acetyl-ADP-ribose Deacetylase Activity Ubiquitin-modified Protein Reader Activity Action Potential Propagation Neuronal Action Potential Propagation	Intermediate Filament Keratin Filament Identical Protein Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Positive Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Positive Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of MRNA Splicing, Via Spliceosome Heterotrimeric G-protein Complex Spliceosomal Complex Regulation Of RNA Splicing Regulation Of Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of RNA Splicing Regulation Of Membrane Repolarization During Action Potential Nucleic Acid Binding MRNA Metabolic Process MRNA Processing Guanyl Nucleotide Binding Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Regulation Of MRNA Metabolic Process Nucleolus Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of Potassium Ion Transport Nitric Oxide Biosynthetic Process G-protein Beta/gamma-subunit Complex Binding Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization RNA Splicing Protein Binding
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