ELAVL4 and GAP43

Number of citations of the paper that reports this interaction (PMID 12034726)
16

Data Source:
HPRD (in vitro)

		ELAVL4	GAP43
Gene Name		ELAV like neuron-specific RNA binding protein 4	growth associated protein 43
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Plasma Membrane Postsynaptic Density Cell Junction Axon Filopodium Membrane Growth Cone Membrane
	Molecular Function	Nucleotide Binding RNA Binding MRNA 3'-UTR Binding AU-rich Element Binding	Protein Binding Calmodulin Binding
	Biological Process	RNA Processing MRNA Processing	Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Response To Wounding Glial Cell Differentiation Axon Choice Point Recognition Regulation Of Growth Tissue Regeneration Cell Fate Commitment Regulation Of Filopodium Assembly Axon Development
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Breast size ( 22747683)
Protein-Protein Interactions		6 interactors: ELAVL2 EWSR1 GAP43 NFX1 NXF1 PHF20L1	8 interactors: CALM1 CSNK2A1 ELAVL4 PLCD1 PRKCB PRKCD RABEP1 SPTAN1
Entrez ID		1996	2596
HPRD ID		01343	01198
Ensembl ID		ENSG00000162374	ENSG00000172020
Uniprot IDs		B1APY9 P26378	P17677 Q5U058
PDB IDs		1FXL 1G2E
Enriched GO Terms of Interacting Partners?			Vascular Endothelial Growth Factor Receptor Signaling Pathway Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Protein Dephosphorylation Platelet Activation Negative Regulation Of Insulin Receptor Signaling Pathway Peptidyl-threonine Phosphorylation Positive Regulation Of Dephosphorylation Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Transporter Activity Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Insulin Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Actin Filament Polymerization Execution Phase Of Apoptosis Positive Regulation Of Phospholipase Activity Blood Coagulation Hemostasis Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Negative Regulation Of Protein Polymerization Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Immune Response-regulating Signaling Pathway Positive Regulation Of Phospholipid Catabolic Process Histone H3-T6 Phosphorylation Regulation Of Body Fluid Levels Regulation Of Dephosphorylation Wound Healing Negative Regulation Of Protein Complex Assembly Interleukin-10 Production Phosphate-containing Compound Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway B Cell Activation Cell Activation Response To Wounding Negative Regulation Of Cytoskeleton Organization Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Filopodium Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Actin Filament Polymerization Interleukin-12 Production
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