GARIN6 and RAB4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GARIN6	RAB4B
Description		golgi associated RAB2 interactor family member 6	RAB4B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component		Endosome Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Secretory Granule Membrane Early Endosome Membrane Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process		Protein Transport Vesicle-mediated Transport Regulation Of Endocytosis Rab Protein Signal Transduction Endosomal Vesicle Fusion Early Endosome To Golgi Transport D-glucose Import
Pathways			Neutrophil degranulation RAB geranylgeranylation MET receptor recycling
Drugs
Diseases
GWAS			Carotid intima media thickness (mean) ( 31801372) Chronic obstructive pulmonary disease ( 22080838 28166215) Emphysema imaging phenotypes ( 26030696) Eosinophil percentage of white cells ( 32888494) Hematocrit ( 32888494) Hemoglobin ( 32888494) Kawasaki disease ( 22081228) Red blood cell count ( 32888494) Smoking behaviour (cigarettes smoked per day) ( 30617275)
Interacting Genes		20 interacting genes: BANP CYSRT1 DNAJB9 FHL3 FHL5 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-8 KRTAP3-2 NBPF19 NOTCH2NLA P4HB PDLIM7 RAB14 RAB2A RAB2B RAB4A RAB4B	9 interacting genes: BOLA2 BOLA2B CDC45 EXOC5 GARIN6 RAB7A RABAC1 RABEP1 VPS52
Entrez ID		196472	53916
HPRD ID		17539	11473
Ensembl ID		ENSG00000180219	ENSG00000167578
Uniprot IDs		Q8NEG0	P61018
PDB IDs			2O52
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament G Protein Activity Insulin-responsive Compartment GTPase Activity Structural Constituent Of Skin Epidermis Structural Molecule Activity GTP Binding Intermediate Filament Organization GDP Binding Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Rab Protein Signal Transduction Early Endosome To Golgi Transport Endosomal Vesicle Fusion Vesicle Fusion Vesicle-mediated Transport Organelle Membrane Fusion Golgi Vesicle Transport Organelle Fusion Z Disc Recycling Endosome Epidermis Development Membrane Fusion Cytoplasmic Vesicle Membrane Organelle Organization Extracellular Exosome Early Endosome Membrane Autophagosome Membrane Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Procollagen-proline 4-dioxygenase Complex Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network	Vesicle-mediated Transport To The Plasma Membrane Post-Golgi Vesicle-mediated Transport Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly Iron-sulfur Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding Localization Within Membrane Protein Localization To Cell Periphery Cell Redox Homeostasis Golgi Vesicle Transport Embryonic Ectodermal Digestive Tract Development Synaptic Vesicle Recycling Via Endosome Protein Localization To Membrane Mitotic DNA Replication Preinitiation Complex Assembly Golgi To Plasma Membrane Transport Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Binding Endocytic Recycling Negative Regulation Of Intralumenal Vesicle Formation Membrane Docking Epidermal Growth Factor Catabolic Process Intracellular Monoatomic Ion Homeostasis Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Intracellular Monoatomic Cation Homeostasis DNA Replication Preinitiation Complex Retrograde Transport, Endosome To Golgi Protein Transport Monoatomic Cation Homeostasis Lipophagy DNA Replication Preinitiation Complex Assembly Monoatomic Ion Homeostasis Lysosomal Transport Cytosolic Transport Vesicle-mediated Transport Negative Regulation Of Exosomal Secretion Intracellular Chemical Homeostasis Recycling Endosome GARP Complex EARP Complex Ectodermal Cell Differentiation Protein To Membrane Docking Glutamatergic Synapse Regulation Of Endosome Organization Membrane Fusion Establishment Of Protein Localization Alveolar Lamellar Body Vacuolar Transport Cellular Homeostasis Phagosome Acidification Membrane Organization
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