GARIN6 and RAB14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GARIN6	RAB14
Description		golgi associated RAB2 interactor family member 6	RAB14, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Rough Endoplasmic Reticulum Golgi Apparatus Golgi Stack Trans-Golgi Network Cytosol Plasma Membrane Cilium Endomembrane System Membrane Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Myosin V Binding
	Biological Process		Phagolysosome Assembly Intracellular Protein Transport Golgi To Endosome Transport Fibroblast Growth Factor Receptor Signaling Pathway Protein Transport Vesicle-mediated Transport Endocytic Recycling Regulation Of Protein Localization Endosomal Vesicle Fusion Early Endosome To Golgi Transport Defense Response To Bacterium Regulation Of Embryonic Development Intracellular Transport Phagosome Maturation
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS			Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
Interacting Genes		20 interacting genes: BANP CYSRT1 DNAJB9 FHL3 FHL5 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-8 KRTAP3-2 NBPF19 NOTCH2NLA P4HB PDLIM7 RAB14 RAB2A RAB2B RAB4A RAB4B	13 interacting genes: ADRB2 APP ARL8B CHM EXOC5 GARIN6 OCRL OPTN RAB11FIP5 RBSN RUFY1 SH3BP5L SMURF2
Entrez ID		196472	51552
HPRD ID		17539	06693
Ensembl ID		ENSG00000180219	ENSG00000119396
Uniprot IDs		Q8NEG0	P61106
PDB IDs			1Z0F 4D0G 4DRZ
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament G Protein Activity Insulin-responsive Compartment GTPase Activity Structural Constituent Of Skin Epidermis Structural Molecule Activity GTP Binding Intermediate Filament Organization GDP Binding Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Rab Protein Signal Transduction Early Endosome To Golgi Transport Endosomal Vesicle Fusion Vesicle Fusion Vesicle-mediated Transport Organelle Membrane Fusion Golgi Vesicle Transport Organelle Fusion Z Disc Recycling Endosome Epidermis Development Membrane Fusion Cytoplasmic Vesicle Membrane Organelle Organization Extracellular Exosome Early Endosome Membrane Autophagosome Membrane Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Procollagen-proline 4-dioxygenase Complex Neurotransmitter Receptor Transport Postsynaptic Membrane To Endosome Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network	Vesicle-mediated Transport Endosome Early Endosome Membrane Early Endosome To Golgi Transport Early Endosome Small GTPase Binding Golgi Vesicle Transport Cellular Response To Amyloid-beta Response To Amyloid-beta Innate Immune Response Response To Mechanical Stimulus Positive Regulation Of CAMP/PKA Signal Transduction Golgi-associated Vesicle Defense Response To Symbiont Defense Response To Gram-negative Bacterium Protein Transport Endosomal Vesicle Fusion Cellular Localization Defense Response To Other Organism Retrograde Transport, Endosome To Golgi Platelet Alpha Granule Post-Golgi Vesicle-mediated Transport Neuronal Dense Core Vesicle Defense Response To Bacterium Lysosomal Transport Establishment Of Protein Localization Cytosolic Transport Recycling Endosome Amyloid Fibril Formation Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Ligand-gated Ion Channel Signaling Pathway Vacuolar Transport Negative Regulation Of Cell Communication Positive Regulation Of Mini Excitatory Postsynaptic Potential Negative Regulation Of Signaling Amyloid-beta Complex Regulation Of Extrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Response To Bacterium Positive Regulation Of Nitric Oxide Metabolic Process Negative Regulation Of Blood Coagulation, Common Pathway Membrane Organization Regulation Of Plasma Membrane Raft Polarization Phosphatidylinositol 3-kinase Catalytic Subunit Binding
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