DPAGT1 and SLC33A2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DPAGT1	SLC33A2
Description		dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	solute carrier family 33 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Intracellular Membrane-bounded Organelle	Membrane
	Molecular Function	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Identical Protein Binding Metal Ion Binding	Protein Binding Transmembrane Transporter Activity
	Biological Process	Protein Glycosylation Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process	Transmembrane Transport
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective DPAGT1 causes CDG-1j, CMSTA2
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS		Estimated glomerular filtration rate ( 31152163) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		2 interacting genes: LSM8 SLC33A2	10 interacting genes: APPBP2 AQP6 DPAGT1 KRTAP10-6 MDFI MMGT1 PCDHGC3 PTAFR SLC7A8 UBE2J1
Entrez ID		1798	113655
HPRD ID		01879	14003
Ensembl ID		ENSG00000172269	ENSG00000167700
Uniprot IDs		A0A804HI18 A0A804HKZ3 Q9H3H5	Q96ES6
PDB IDs		5LEV 5O5E 6BW5 6BW6 6FM9 6FWZ 6JQ3
Enriched GO Terms of Interacting Partners?			PH-gated Chloride Channel Activity Monoatomic Anion Channel Activity Nitrate Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Ammonium Transmembrane Transport Ammonium Channel Activity Nitrate Transmembrane Transport Renal Water Transport Cytoplasmic Vesicle Membrane Carbon Dioxide Transmembrane Transport UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Glycoprotein Biosynthetic Process Protein N-linked Glycosylation Platelet Activating Factor Receptor Activity G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Activity Inositol Trisphosphate Metabolic Process Lipopolysaccharide Immune Receptor Activity L-alanine Transport Tryptophan Transport Branched-chain Amino Acid Transport Proline Transmembrane Transport Aromatic Amino Acid Transport L-alanine Transmembrane Transport L-leucine Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity L-leucine Transport L-leucine Import Across Plasma Membrane Glycine Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-alanine Import Across Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Valine Transport Negative Regulation Of Protein Exit From Endoplasmic Reticulum Hrd1p Ubiquitin Ligase Complex Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence EMC Complex Inorganic Cation Transmembrane Transporter Activity Cobalt Ion Transmembrane Transporter Activity Cobalt Ion Transport Ferrous Iron Transmembrane Transporter Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Organic Cation Transmembrane Transporter Activity Thyroid Hormone Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?