ZNF675 and LMO4

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		ZNF675	LMO4
Gene Name		zinc finger protein 675	LIM domain only 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Perinuclear Region Of Cytoplasm	Transcription Factor Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding	Enhancer Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Cytokine-mediated Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of JUN Kinase Activity Bone Resorption Negative Regulation Of Osteoclast Differentiation Negative Regulation Of JNK Cascade Negative Regulation Of Interleukin-1-mediated Signaling Pathway Negative Regulation Of Transcription Regulatory Region DNA Binding	Neural Tube Closure Ventricular Septum Development Transcription From RNA Polymerase II Promoter Ventral Spinal Cord Interneuron Differentiation Spinal Cord Motor Neuron Differentiation Spinal Cord Association Neuron Differentiation Negative Regulation Of Protein Complex Assembly Regulation Of Cell Fate Specification Positive Regulation Of Transcription From RNA Polymerase II Promoter Thymus Development Regulation Of Cell Activation
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Response to TNF antagonist treatment ( 18615156) White blood cell types ( 21738478)
Protein-Protein Interactions		2 interactors: LMO4 TRAF6	53 interactors: AES AMOT AMOTL2 BANP BRCA1 CALCOCO2 CCDC102B CEP170P1 CSNK2B DDB1 DEAF1 ERCC6L GABPB1 GADD45A GOLGA2 GRHL2 GSK3B ITSN1 KANK2 KIAA1958 KIF3B KPNA1 KRT15 KRT31 KRT40 LDB1 LDB2 MERTK MTA1 NFYC NHLH1 NONO PDE4DIP PITPNB PLK1 PPARG RBBP8 RBPMS RPS6KA6 SEC24D SMAD4 SMAD9 TCF21 TCF4 TFIP11 TINAGL1 TNFSF11 TP53BP2 TSEN15 VPS52 ZBTB43 ZNF397 ZNF675
Entrez ID		171392	8543
HPRD ID		18193	09122
Ensembl ID		ENSG00000197372	ENSG00000143013
Uniprot IDs		Q8TD23	P61968
PDB IDs			2L4Z
Enriched GO Terms of Interacting Partners?		Neural Tube Closure Neural Tube Formation Embryonic Epithelial Tube Formation Epithelial Tube Formation Tube Formation Morphogenesis Of Embryonic Epithelium Neural Tube Development Epithelial Tube Morphogenesis Tube Morphogenesis Regulation Of Cell Activation Morphogenesis Of An Epithelium Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Transcription Regulatory Region DNA Binding Embryonic Morphogenesis Tissue Morphogenesis Immune System Development Tube Development Positive Regulation Of Interleukin-12 Biosynthetic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Interleukin-6 Biosynthetic Process Spinal Cord Association Neuron Differentiation Regulation Of Immunoglobulin Secretion Regulation Of Interleukin-12 Biosynthetic Process Membrane Protein Intracellular Domain Proteolysis Interleukin-1-mediated Signaling Pathway Positive Regulation Of T Cell Cytokine Production Regulation Of Cell Fate Specification Regulation Of Lipopolysaccharide-mediated Signaling Pathway Ventral Spinal Cord Interneuron Differentiation Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Dorsal Spinal Cord Development Regulation Of Transcription Regulatory Region DNA Binding Anatomical Structure Formation Involved In Morphogenesis Myeloid Dendritic Cell Differentiation Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of T Cell Cytokine Production Epithelium Development Positive Regulation Of Osteoclast Differentiation Myeloid Dendritic Cell Activation T-helper 1 Type Immune Response Embryo Development Activation Of NF-kappaB-inducing Kinase Activity Protein K63-linked Ubiquitination Regulation Of Cell Fate Commitment Positive Regulation Of NIK/NF-kappaB Signaling Membrane Protein Proteolysis Positive Regulation Of Interleukin-2 Production Bone Resorption	Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Tissue Development Negative Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Multicellular Organismal Development Developmental Process Gene Expression Regulation Of Binding Regulation Of Gene Expression Anatomical Structure Development Cellular Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Epithelium Development Negative Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Embryo Development Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Wnt Signaling Pathway Negative Regulation Of Gene Expression Positive Regulation Of Nucleocytoplasmic Transport Embryo Development Ending In Birth Or Egg Hatching Regulation Of Signal Transduction Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Biosynthetic Process Regulation Of DNA Methylation Cell Cycle Somatic Stem Cell Maintenance Regulation Of Protein Binding Anatomical Structure Morphogenesis
Tagcloud ?			arrays attenuated cisplatin cochlea cochlear collectively custom downstream esr1 facilitates immunoblots insights interactomes jak1 machinery mediating modulating modulation nitration otoprotective ototoxicity partners pivotal player relaying stat stat3 trolox wistar
Tagcloud (Difference) ?			arrays attenuated cisplatin cochlea cochlear collectively custom downstream esr1 facilitates immunoblots insights interactomes jak1 machinery mediating modulating modulation nitration otoprotective ototoxicity partners pivotal player relaying stat stat3 trolox wistar
Tagcloud (Intersection) ?