BHLHA15 and TCF3

Number of citations of the paper that reports this interaction (PMID 9073453)
15

Data Source:
HPRD (in vivo, in vitro)

		BHLHA15	TCF3
Gene Name		basic helix-loop-helix family, member a15	transcription factor 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nuclear Nucleosome Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Protein Complex RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Homodimerization Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Enhancer Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Repressing Transcription Factor Binding Vitamin D Response Element Binding E-box Binding
	Biological Process	Transcription, DNA-templated Mitochondrial Calcium Ion Transport Golgi Organization G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Negative Regulation Of Myotube Differentiation Calcium-mediated Signaling Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Glucose Starvation Glucose Homeostasis Positive Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Distribution Of Mitochondria Cell Maturation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation B Cell Lineage Commitment Transcription, DNA-templated Regulation Of Transcription, DNA-templated B Cell Differentiation Positive Regulation Of B Cell Proliferation Response To Lipopolysaccharide T Cell Differentiation In Thymus Immunoglobulin V(D)J Recombination Response To Drug Muscle Cell Differentiation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Neuron Differentiation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Development Peyer's Patch Development Protein Stabilization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Muscle Cell Differentiation Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: MYOD1 TCF3	62 interactors: AEBP1 ASCL3 BHLHA15 CALM1 CALM3 CBFA2T3 CREBBP CTNNB1 DAXX ELK3 EP300 FERD3L HAND1 HAND2 HOXA1 ID1 ID2 ID3 KAT2A KAT2B LMX1A LMX1B LYL1 MAPK1 MAPK3 MAPKAPK2 MAPKAPK3 MAX MDFI MEN1 MSC MYF5 MYF6 MYOD1 MYOG NEDD9 NHLH1 PDX1 PRKACA PSMD4 PSMD9 RALGAPA1 RPL37 RUFY1 RUNX1T1 SKP2 SRF SUPT3H TADA2A TAL1 TAL2 TCAF1 TCF12 TCF21 TCF4 TFPT TLE1 TRRAP TWIST1 UBE2I USF1 VDR
Entrez ID		168620	6929
HPRD ID		16356	00918
Ensembl ID		ENSG00000180535	ENSG00000071564
Uniprot IDs		Q7RTS1	P15923 Q2TB39
PDB IDs			1HLH 2YPA 2YPB 3U5V
Enriched GO Terms of Interacting Partners?		Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Muscle Cell Differentiation Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Muscle Cell Differentiation Peptidyl-lysine Modification Cell Fate Commitment Myoblast Fate Determination Myotube Differentiation Involved In Skeletal Muscle Regeneration Skeletal Muscle Fiber Adaptation Muscle Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Histone Modification Axial Mesoderm Morphogenesis Positive Regulation Of Skeletal Muscle Tissue Regeneration Positive Regulation Of Cell Development Muscle Structure Development Immunoglobulin V(D)J Recombination Positive Regulation Of Skeletal Muscle Fiber Development Myoblast Fate Commitment Chromatin Modification Axial Mesoderm Development Skeletal Muscle Adaptation B Cell Lineage Commitment Chromatin Organization Peyer's Patch Development Response To Lipid Regulation Of Cell Development Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Muscle Cell Fate Commitment Positive Regulation Of Myoblast Differentiation Natural Killer Cell Differentiation Positive Regulation Of Myoblast Fusion Cellular Response To Estradiol Stimulus Anterior/posterior Axis Specification, Embryo Peptidyl-amino Acid Modification Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal Muscle Fiber Development Regulation Of Stem Cell Maintenance V(D)J Recombination Skeletal Muscle Tissue Regeneration	RNA Biosynthetic Process Transcription, DNA-templated Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Organ Development Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process System Development Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Anatomical Structure Development Multicellular Organismal Development Developmental Process Embryo Development Tissue Development Organ Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Binding Embryonic Morphogenesis Cell Differentiation Anatomical Structure Morphogenesis Embryonic Organ Development
Tagcloud ?			advantageous characterize chimpanzee crebbp eleven ep300 evolution fgf2 germ gorilla hdac3 macaque macaques mapped microarrays orangutan organs partners primate prkd3 profiled profiling proteomics regard runx1 runx2 satb2 testis yap1
Tagcloud (Difference) ?			advantageous characterize chimpanzee crebbp eleven ep300 evolution fgf2 germ gorilla hdac3 macaque macaques mapped microarrays orangutan organs partners primate prkd3 profiled profiling proteomics regard runx1 runx2 satb2 testis yap1
Tagcloud (Intersection) ?