THAP5 and FAM175B

Number of citations of the paper that reports this interaction (PMID 21195082)
7

Data Source:
BioGRID (two hybrid)

		THAP5	FAM175B
Gene Name		THAP domain containing 5	family with sequence similarity 175, member B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm BRISC Complex
	Molecular Function	Protease Binding DNA Binding Metal Ion Binding	Polyubiquitin Binding
	Biological Process	Cell Cycle Negative Regulation Of Cell Cycle	Cellular Response To Freezing
Pathways
Drugs
Diseases
GWAS		Smoking behavior ( 22006218)
Protein-Protein Interactions		2 interactors: FAM175B SKIL	4 interactors: SMURF2 THAP5 UBC USP7
Entrez ID		168451	23172
HPRD ID		15498	13783
Ensembl ID		ENSG00000177683	ENSG00000165660
Uniprot IDs		Q7Z6K1	Q15018
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Freezing Cellular Response To Cold Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Heterotrimerization Protein Homotrimerization Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Protein Catabolic Process Protein Catabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Canonical Wnt Signaling Pathway Cellular Macromolecule Catabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Canonical Wnt Signaling Pathway DNA-templated Transcription, Initiation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Wnt Signaling Pathway Proteolysis Ubiquitin-dependent SMAD Protein Catabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Maintenance Of DNA Methylation Regulation Of Protein Catabolic Process Catabolic Process Viral Protein Processing Negative Regulation Of Cell Cycle Viral Process Histone Deubiquitination Protein Ubiquitination Cellular Response To Growth Factor Stimulus DNA Repair Response To Growth Factor Notch Receptor Processing Protein Modification By Small Protein Conjugation Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Proteolysis Glycogen Biosynthetic Process Intracellular Transport Of Virus Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Transcription-coupled Nucleotide-excision Repair Cellular Response To DNA Damage Stimulus
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