ABRAXAS2

Description		abraxas 2, BRISC complex subunit
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GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Microtubule Midbody Spindle Pole Centrosome Ciliary Basal Body Microtubule Minus-end BRISC Complex
	Molecular Function	Protein Binding Microtubule Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Mitotic Cell Cycle Response To Ischemia Chromosome Segregation Attachment Of Spindle Microtubules To Kinetochore Cell Division Protein K63-linked Deubiquitination Mitotic Spindle Assembly
Pathways		Metalloprotease DUBs
Drugs
Diseases
GWAS		Bone mineral content ( 31790847)
Novel Interacting Genes		1 novel interacting genes: ATE1
Interacting Genes		7 interacting genes: DCUN1D1 NUMA1 OGT SMURF2 THAP5 UBC USP7
Entrez ID		23172
HPRD ID		13783
Ensembl ID		ENSG00000165660
Uniprot IDs		Q15018
PDB IDs		6H3C 6R8F 8PVY 8PY2
Enriched GO Terms of Interacting Partners?		Protein Modification Process Post-translational Protein Modification Protein Modification By Small Protein Conjugation Proteolysis Protein Ubiquitination Cortical Microtubule Anastral Spindle Assembly Nucleoplasm Regulation Of Cellular Response To Growth Factor Stimulus Cytoplasmic Microtubule Bundle Positive Regulation Of Protein Localization To Spindle Pole Body Nucleus Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Mitotic Spindle Elongation Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Gluconeogenesis Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Arginyl-tRNA--protein Transferase Activity Protein Metabolic Process Negative Regulation Of Proteolysis Involved In Protein Catabolic Process TOR Signaling Protein Localization To Vacuole Lateral Cell Cortex Regulation Of TORC1 Signaling Regulation Of Glucose Metabolic Process Protein Arginylation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ubiquitin Ligase Complex Regulation Of BMP Signaling Pathway Cell Cortex Region Regulation Of Cellular Localization Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Protein Catabolic Process Protein O-acetylglucosaminyltransferase Activity Mitotic Spindle Astral Microtubule Modification-dependent Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Microtubule Bundle Regulation Of Protein Localization To Cell Periphery Regulation Of TOR Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway Ubiquitin-like Protein Binding
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