LCA5 and TXLNA

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		LCA5	TXLNA
Description		lebercilin LCA5	taxilin alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Mitochondrion Centrosome Cytoskeleton Cilium Axoneme Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection	Extracellular Region Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding Syntaxin Binding
	Biological Process	Protein Transport Intraciliary Transport Photoreceptor Cell Maintenance	Exocytosis B Cell Activation
Pathways			Other interleukin signaling
Drugs
Diseases		Leber congenital amaurosis (LCR)
GWAS		Glucose homeostasis traits ( 25524916) Hoarding ( 21302353) Presence of antiphospholipid antibodies ( 23509613)
Interacting Genes		6 interacting genes: GCC1 RCOR3 SRPK2 SUFU TFIP11 TXLNA	95 interacting genes: AXIN2 AZI2 BIN3 BRCA1 BRMS1L BTF3 BTF3L4 CBY2 CCDC112 CCDC136 CCDC146 CCDC196 CCDC33 CCDC57 CCHCR1 CDC5L CDR2 CEBPA CEP44 CEP57 CEP57L1 CEP63 CFAP53 DEUP1 DMAP1 DRC4 DTNB EIF4ENIF1 EPN2 FAM81A FAM9A GOLGA2 GOLGA6A GORASP2 HAUS3 HYPK IKBKG KANK2 KIAA1328 KRT13 KRT15 KRT20 KRT24 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 KRT75 LCA5 LZTS1 MBIP MCC MEOX1 MEOX2 MIS18A NACA NDC80 NKAPD1 NMI NSMCE2 NUP62 OLIG2 PIAS2 PPFIA1 PPP1R13B PRDM16 PRPF3 RASSF8 RCOR3 RINT1 SIKE1 SLC25A21-AS1 SMARCE1 SNCA SNF8 SORBS3 SREK1 STMN2 STX1A STX1B STX3 STX4 TBC1D1 TCL1A TFIP11 TNIP1 TP53BP2 TTC33 TXLNB USHBP1 UTP14C WASHC1 WASHC3
Entrez ID		167691	200081
HPRD ID		10791	09408
Ensembl ID		ENSG00000135338	ENSG00000084652
Uniprot IDs		A0A384MDJ7 Q86VQ0	P40222
PDB IDs
Enriched GO Terms of Interacting Partners?		Spliceosomal Complex Disassembly U2-type Post-mRNA Release Spliceosomal Complex Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Regulation Of Cellular Response To Drug Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Positive Regulation Of Cellular Response To Drug Positive Regulation Of Response To Drug Nuclear Speck Organization GLI-SUFU Complex Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Protection From Non-homologous End Joining At Telomere Transcription Corepressor Activity Regulation Of Response To Drug Spinal Cord Dorsal/ventral Patterning Golgi Trans Cisterna R-loop Processing	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Organelle Organization Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Structural Molecule Activity Microtubule Organizing Center Organization Protein Binding Cytoskeleton Organization Centriole Assembly Centriole Centrosome Cycle Centriole Replication Epithelial Cell Differentiation Morphogenesis Of An Epithelium Cytoplasm Membraneless Organelle Assembly Negative Regulation Of Protein Localization To Endoplasmic Reticulum SNARE Binding Microtubule-based Process HMG Box Domain Binding SNARE Complex Assembly Organelle Assembly SNAP Receptor Activity Nascent Polypeptide-associated Complex Tissue Morphogenesis SNARE Complex Exocytosis Cell Differentiation Negative Regulation Of Cell Cycle Cytosol Positive Regulation Of Neurotransmitter Secretion Identical Protein Binding Neurotransmitter Transport Regulation Of Cell Cycle Spindle Pole Centrosome Somite Specification De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation Cellular Developmental Process Vesicle Docking De Novo Centriole Assembly Microtubule Binding Establishment Of Protein Localization Manchette Assembly Regulation Of Cytoskeleton Organization
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