DCLK2 and TSC22D3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		DCLK2	TSC22D3
Gene Name		doublecortin-like kinase 2	TSC22 domain family, member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton	Nucleus Cytosol
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding	Sequence-specific DNA Binding Transcription Factor Activity MRF Binding
	Biological Process	Protein Phosphorylation Intracellular Signal Transduction	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Response To Osmotic Stress Body Fluid Secretion Ion Transmembrane Transport Negative Regulation Of Skeletal Muscle Tissue Development Transmembrane Transport Negative Regulation Of Activation-induced Cell Death Of T Cells
Pathways			Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS		Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		1 interactors: TSC22D3	15 interactors: C19orf57 DCLK2 FOS HPCAL4 JUN MAD1L1 MDM2 MTA2 NFKB1 NFKB2 PLEKHF2 RAF1 RELA SUMO1 TP53
Entrez ID		166614	1831
HPRD ID		13122	04266
Ensembl ID		ENSG00000170390	ENSG00000157514
Uniprot IDs		Q8N568	Q5JRJ2 Q99576
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Activation-induced Cell Death Of T Cells Regulation Of Activation-induced Cell Death Of T Cells Negative Regulation Of Skeletal Muscle Tissue Development Negative Regulation Of T Cell Apoptotic Process Regulation Of T Cell Apoptotic Process Negative Regulation Of Striated Muscle Tissue Development Negative Regulation Of Muscle Organ Development Negative Regulation Of Leukocyte Apoptotic Process Regulation Of Lymphocyte Apoptotic Process Regulation Of Skeletal Muscle Tissue Development Response To Osmotic Stress Body Fluid Secretion Regulation Of Striated Muscle Tissue Development	Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Fc-epsilon Receptor Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Innate Immune Response Fc Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Immune Response Innate Immune Response-activating Signal Transduction Regulation Of Immune Response Activation Of Innate Immune Response Cellular Response To Growth Factor Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Growth Factor Negative Regulation Of Cellular Metabolic Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Oxidative Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Immune System Process Intracellular Signal Transduction Negative Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Defense Response Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Immune System Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Alkaloid Response To Abiotic Stimulus NIK/NF-kappaB Signaling Response To Cytokine Protein Localization To Nucleus Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?			2xglucocorticoid 2xgre agonism agonists beas bronchial budesonide cdkn1c ciclesonide combat dexamethasone dusp1 fluticasone formoterol furoate glucocorticoid glucocorticoids gre gsk9027 gw870086x ikk2 nr3c1 phosphoinositide propionate reporter rgs2 ru24858 suboptimal viii
Tagcloud (Difference) ?			2xglucocorticoid 2xgre agonism agonists beas bronchial budesonide cdkn1c ciclesonide combat dexamethasone dusp1 fluticasone formoterol furoate glucocorticoid glucocorticoids gre gsk9027 gw870086x ikk2 nr3c1 phosphoinositide propionate reporter rgs2 ru24858 suboptimal viii
Tagcloud (Intersection) ?