PARP15 and NRM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PARP15	NRM
Description		poly(ADP-ribose) polymerase family member 15	nurim
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nuclear Envelope Nuclear Inner Membrane Membrane Nuclear Membrane
	Molecular Function	Transcription Corepressor Activity NAD+ Poly-ADP-ribosyltransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity Nucleotidyltransferase Activity NAD+ Binding NAD+-protein-aspartate ADP-ribosyltransferase Activity NAD+-protein-glutamate ADP-ribosyltransferase Activity NAD+-protein Mono-ADP-ribosyltransferase Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression Protein Poly-ADP-ribosylation
Pathways
Drugs		N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
Diseases
GWAS		Major depressive disorder ( 22472876) Periodontitis (CDC/AAP) ( 24024966)	Alcohol dependence symptom count ( 27151647) Autism spectrum disorder or schizophrenia ( 28540026) Height ( 31217584) Itch intensity from mosquito bite ( 28199695) Number of sexual partners ( 30643258)
Interacting Genes		2 interacting genes: APP NRM	51 interacting genes: AGR3 ANK1 AQP6 ARL13B ATP6V0B BIK CLRN1 CNR2 CPLX4 CREB3L1 CYB5R3 CYBC1 ERGIC3 ERP29 FAM209A FCER1G FFAR2 FRMD3 GOLT1A GORAB GPR151 GPR42 GPX8 HDAC11 HHLA2 HSD17B13 KIR2DL3 MFF MGST3 MRM1 OPN1LW PARP15 PEX12 RETREG3 RHBDD2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A2 SLC10A6 SLC18A1 SLC30A2 SLC35H1 SPAG4 SSMEM1 STX1A SUN2 TMEM52B TMX2 TRIM59
Entrez ID		165631	11270
HPRD ID		08811	10120
Ensembl ID		ENSG00000173200	ENSG00000137404
Uniprot IDs		B7ZL48 C9J7L3 Q460N3	A0A1U9X845 B3KQU6 Q8IXM6
PDB IDs		3BLJ 3GEY 3V2B 4F0E 6EK3 6RY4 7F41 7F42 7F43 7OQQ 7OSP 7OSS 7OSX 7OTF 7OTH 7OUW 7OUX 7PW3 7PWA 7PWC 7PWK 7PWL 7PWM 7PWP 7PWQ 7PWR 7PWS 7PWU 7PWW 7PX6 7PX7 7R3O 7R4A 7R5D 7Z1V 7Z1W 7Z1Y 7Z2O 7Z2Q 7Z41
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding	Membrane Protein Binding Endoplasmic Reticulum Bile Acid:sodium Symporter Activity
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