CEP20 and CCDC116

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CEP20	CCDC116
Description		centrosomal protein 20	coiled-coil domain containing 116
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytoskeleton Cilium Motile Cilium Centriolar Satellite Ciliary Basal Body Cell Projection	Cytoplasm Centrosome Cytoskeleton
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Cell Projection Organization Microtubule Anchoring Cilium Assembly
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233 28067908) Ulcerative colitis ( 28067908) White blood cell count ( 32888494)
Interacting Genes		8 interacting genes: CCDC116 S100A1 S100A11 S100A2 S100A4 S100A6 S100B TUBA1A	32 interacting genes: AKAP9 BEX3 CARD10 CCDC85B CDCA7L CEP20 CEP44 COG6 CSNK2A1 CTAG1A CTAG1B FAM9B GOLGA6L9 HSF2BP IGFBP6 KRT31 KRT40 KRTAP4-12 MDFI MEIS3 MTUS2 NUTM1 PKNOX2 PPP1R16A RASSF10 SLC2A4 TADA2A TFIP11 TRAF1 USHBP1 ZMYND12 ZNF655
Entrez ID		123811	164592
HPRD ID		08096	08203
Ensembl ID		ENSG00000133393	ENSG00000161180
Uniprot IDs		I3L269 I3L2N4 I3L4V2 I3NI25 Q96NB1	Q8IYX3
PDB IDs
Enriched GO Terms of Interacting Partners?		Calcium-dependent Protein Binding S100 Protein Binding Calcium Ion Binding RAGE Receptor Binding Ruffle Identical Protein Binding Transition Metal Ion Binding Metal Ion Binding Protein Homodimerization Activity Neuron Projection Morphogenesis Cell Projection Morphogenesis Extracellular Region Glial Cell Differentiation Memory Axonogenesis Pyramidal Neuron Differentiation Cerebellar Cortex Morphogenesis Response To Anesthetic Response To Methylmercury Sympathetic Neuron Projection Extension
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