TMEM92 and DERL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM92	DERL3
Description		transmembrane protein 92	derlin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding
	Biological Process		Protein N-linked Glycosylation Via Asparagine Endoplasmic Reticulum Unfolded Protein Response ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways			ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS		Heel bone mineral density ( 28869591 30598549)	Ejection fraction ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Left ventricular internal dimension in systole ( 29403010) PR interval ( 32439900) S-phenylmercapturic acid levels in smokers ( 26959369)
Interacting Genes		3 interacting genes: DERL3 RTP2 YAP1	19 interacting genes: EHHADH GAD2 GNLY GPR101 IL27RA MELTF NDRG4 PSCA RTP4 SDCBP SERPINA1 SLC13A4 STATH SYT16 TEX29 TMEM179B TMEM31 TMEM92 ULBP2
Entrez ID		162461	91319
HPRD ID		08743	13139
Ensembl ID		ENSG00000167105	ENSG00000099958
Uniprot IDs		Q6UXU6	Q96Q80
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Branch Elongation Of An Epithelium Lateral Mesoderm Development Positive Regulation Of Cardiac Muscle Cell Proliferation Cellular Response To Gamma Radiation Intestinal Epithelial Cell Development Bud Elongation Involved In Lung Branching Glandular Epithelial Cell Differentiation Lung Epithelial Cell Differentiation Regulation Of Nephron Tubule Epithelial Cell Differentiation TEAD-YAP Complex Hippo Signaling Notochord Development Negative Regulation Of Stem Cell Differentiation Glycolytic Process Through Fructose-6-phosphate Glucose Catabolic Process Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Female Germ Cell Nucleus Polarized Epithelial Cell Differentiation Trophectodermal Cell Differentiation Glycolytic Process Through Glucose-6-phosphate Cardiac Muscle Tissue Regeneration Enterocyte Differentiation Paraxial Mesoderm Development Intestinal Epithelial Cell Differentiation Lung Cell Differentiation Columnar/cuboidal Epithelial Cell Development Negative Regulation Of Epithelial Cell Apoptotic Process Negative Regulation Of Cilium Assembly Axis Elongation Proline-rich Region Binding Interleukin-6-mediated Signaling Pathway Canonical Glycolysis Signal Recognition Particle Binding Protein N-linked Glycosylation Via Asparagine Regulation Of Protein Exit From Endoplasmic Reticulum Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Protein Exit From Endoplasmic Reticulum Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Detection Of Chemical Stimulus Involved In Sensory Perception Of Taste Olfactory Receptor Binding Blastocyst Development Heart Process Response To Progesterone Carbohydrate Derivative Metabolic Process
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