DERL3

Description		derlin 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Signal Recognition Particle Binding Protein Binding Protein-containing Complex Binding
	Biological Process	Protein N-linked Glycosylation Via Asparagine Endoplasmic Reticulum Unfolded Protein Response ERAD Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol
Pathways		ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Diseases
GWAS		Ejection fraction ( 29403010) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Left ventricular internal dimension in systole ( 29403010) PR interval ( 32439900) S-phenylmercapturic acid levels in smokers ( 26959369)
Interacting Genes		19 interacting genes: EHHADH GAD2 GNLY GPR101 IL27RA MELTF NDRG4 PSCA RTP4 SDCBP SERPINA1 SLC13A4 STATH SYT16 TEX29 TMEM179B TMEM31 TMEM92 ULBP2
Entrez ID		91319
HPRD ID		13139
Ensembl ID		ENSG00000099958
Uniprot IDs		Q96Q80
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?