MAGEB6 and SUPV3L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEB6	SUPV3L1
Description		MAGE family member B6	Suv3 like RNA helicase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid Mitochondrial Degradosome
	Molecular Function	Protein Binding	Nucleotide Binding DNA Binding DNA Helicase Activity RNA Binding RNA Helicase Activity Double-stranded RNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity 3'-5' RNA Helicase Activity Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Mitochondrial RNA Catabolic Process Mitochondrial MRNA Catabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process Mitochondrial RNA 3'-end Processing DNA Recombination RNA Catabolic Process Mitochondrion Organization Positive Regulation Of Cell Growth Mitochondrial NcRNA Surveillance Mitochondrial MRNA Surveillance Negative Regulation Of Apoptotic Process Mitochondrial RNA Surveillance
Pathways			Mitochondrial RNA degradation
Drugs
Diseases
GWAS			Facial morphology ( 31763980) Glycemic traits (pregnancy) ( 23903356) Immune reponse to smallpox (secreted IL-1beta) ( 22610502)
Interacting Genes		7 interacting genes: APBA2 ATXN1 HACL1 HTT PHC2 ROBO1 SUPV3L1	7 interacting genes: ADAP1 DSCAM EIF4ENIF1 LZTS2 MAGEB6 RBFOX2 RNF10
Entrez ID		158809	6832
HPRD ID		06628	05493
Ensembl ID		ENSG00000176746	ENSG00000156502
Uniprot IDs		Q8N7X4	B7Z611 Q8IYB8
PDB IDs			3RC3 3RC8 7W1R
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Mitochondrial RNA Surveillance Mitochondrial NcRNA Surveillance Mitochondrial MRNA Surveillance 2-hydroxyacyl-CoA Lyase Activity 2-hydroxyphytanoyl-CoA Lyase Activity Regulation Of CAMKK-AMPK Signaling Cascade Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Aggrephagy Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Lipophagy Learning Positive Regulation Of CAMKK-AMPK Signaling Cascade Negative Regulation Of Negative Chemotaxis Axon Midline Choice Point Recognition Regulation Of Negative Chemotaxis Roundabout Signaling Pathway Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Chemorepulsion Involved In Postnatal Olfactory Bulb Interneuron Migration POZ Domain Binding Positive Regulation Of Mitochondrial RNA Catabolic Process Mitochondrial Degradosome Mitochondrial MRNA Catabolic Process Methyl-branched Fatty Acid Metabolic Process Phytanic Acid Metabolic Process Locomotory Behavior Vocal Learning LRR Domain Binding Heart Induction Axon Choice Point Recognition Negative Regulation Of Chemokine-mediated Signaling Pathway Poly(G) Binding Mitochondrial RNA 3'-end Processing Mitochondrial RNA Catabolic Process 3'-5' RNA Helicase Activity Fatty Acid Alpha-oxidation Thiamine Pyrophosphate Binding Observational Learning Positive Regulation Of Neurogenesis Regulation Of Heart Morphogenesis Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Carbon-carbon Lyase Activity Brain Development Profilin Binding Protein Targeting To Peroxisome Axon Guidance Receptor Activity Learning Or Memory Endocardial Cushion Formation Positive Regulation Of Nervous System Development Nuclear Inclusion Body
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