TMEM74 and TMEM42

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM74	TMEM42
Description		transmembrane protein 74	transmembrane protein 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Lysosome Lysosomal Membrane Plasma Membrane Membrane Cytoplasmic Vesicle	Membrane
	Molecular Function	Protein Binding Transmembrane Transporter Binding	Protein Binding
	Biological Process	Autophagy Macroautophagy General Adaptation Syndrome, Behavioral Process
Pathways
Drugs
Diseases
GWAS		Male-pattern baldness ( 27182965)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756)
Interacting Genes		7 interacting genes: AQP6 FATE1 LIME1 LMNA MS4A13 SPCS1 TMEM42	56 interacting genes: AQP3 AQP6 BDKRB1 CD79A CPLX4 DTX2 EBP EDA ELOVL4 ERGIC3 FAM174A FAM209A GET1 GJA8 GOLM2 GPR152 GPX8 HSD17B11 HSD17B13 LEPROTL1 LHFPL5 LMNA MFF MGAT5B MMD MMGT1 MRM1 MTIF3 NEMP1 PROP1 PSCA RABAC1 RBPMS REEP1 REEP2 REEP4 RETREG3 RHBDD1 SAR1A SCN3B SEC11C SERINC2 SHISAL1 SLC18A1 SLC34A2 SMIM14 SVOPL TLX3 TM4SF19 TMEM147 TMEM14B TMEM237 TMEM35A TMEM74 VENTX ZDHHC15
Entrez ID		157753	131616
HPRD ID		08702	15540
Ensembl ID		ENSG00000164841	ENSG00000169964
Uniprot IDs		Q96NL1	Q69YG0
PDB IDs
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament Nuclear Pore Localization Signal Peptidase Complex B Cell Receptor Complex Negative Regulation Of Mitochondrial Calcium Ion Concentration Monoatomic Anion Channel Activity Renal Water Transport Negative Regulation Of Mesenchymal Cell Proliferation Virion Assembly Ammonium Channel Activity Signal Peptide Processing Ammonium Transmembrane Transport Ventricular Cardiac Muscle Cell Development	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Steroid Dehydrogenase Activity Endoplasmic Reticulum Organization Establishment Of Protein Localization To Membrane Protein Insertion Into Membrane Protein Insertion Into ER Membrane Acetylcholine Receptor Regulator Activity Renal Water Transport Localization Within Membrane
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