ZSWIM2 and MAGEA11

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ZSWIM2	MAGEA11
Gene Name		zinc finger, SWIM-type containing 2	melanoma antigen family A, 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Protein Self-association	Protein Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: MAGEA11 UBC UBE2U	86 interactors: ACMSD ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 C18orf54 CCDC14 CCDC146 CCDC185 CDC20B CDKN2B CEP76 CLUAP1 COX7A2L CSNK2A1 DIEXF DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A GNPDA1 HOXB5 IL11 IL6ST ILF3 JADE3 KIAA0408 LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 OTUB2 PCBD2 PDE4B PHYH PIN4 PNKD PNKP POLR1D PRDX3 PRKRIP1 PSMF1 RADIL RBM23 SH2D4A SNX20 SNX7 STAR TCEA2 TCEANC TCF25 TEX37 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 USP20 VTA1 WDYHV1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2
Entrez ID		151112	4110
HPRD ID		15902	02281
Ensembl ID		ENSG00000163012	ENSG00000185247
Uniprot IDs		Q8NEG5	G5E962 P43364
PDB IDs		2DIP
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination DNA Repair Protein Modification By Small Protein Conjugation Protein Catabolic Process Viral Protein Processing Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Notch Receptor Processing Virion Assembly DNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Glycogen Biosynthetic Process Intracellular Transport Of Virus Histone Ubiquitination Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cellular Response To Stress Proteolysis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 9 Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Glycogen Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity MyD88-independent Toll-like Receptor Signaling Pathway	Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Gene Expression Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Catabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Metabolic Process Protein Polyubiquitination Negative Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Testosterone Biosynthetic Process Regulation Of Cell Death Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Protein Metabolic Process Rhythmic Process Cell Death Response To Lipopolysaccharide Death Negative Regulation Of Protein Metabolic Process Respiratory Electron Transport Chain Response To Molecule Of Bacterial Origin Regulation Of Cell Cycle Electron Transport Chain Oxidation-reduction Process Negative Regulation Of Catalytic Activity RNA Methylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Apoptotic Process Reproductive Structure Development Positive Regulation Of Gene Expression Reproductive System Development Negative Regulation Of Mitotic Cell Cycle Phase Transition Programmed Cell Death
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