ZNF558 and LZIC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF558	LZIC
Description		zinc finger protein 558	leucine zipper and CTNNBIP1 domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Beta-catenin Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Response To Ionizing Radiation
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS			Resting heart rate ( 27798624)
Interacting Genes		13 interacting genes: APOE CLK2 CSNK2A1 EFEMP2 EIF1AD EXOSC5 GSDMD HEXIM2 LZIC MAD2L2 MFAP1 TIAM1 UBTFL1	3 interacting genes: IKBKG VCP ZNF558
Entrez ID		148156	84328
HPRD ID		15841	14340
Ensembl ID		ENSG00000167785	ENSG00000162441
Uniprot IDs		Q96NG5	Q8WZA0
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phospholipid Efflux Artery Development Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Negative Regulation Of DNA Repair Negative Regulation Of DNA Recombination Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Double-strand Break Repair Microfibril DNA Damage Response, Signal Transduction Resulting In Transcription Positive Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Cell Cycle Process Positive Regulation Of Presynaptic Membrane Organization Chylomicron Remnant Lipid Transport Involved In Lipid Storage Lipoprotein Particle Positive Regulation Of Neurofibrillary Tangle Assembly Discoidal High-density Lipoprotein Particle Regulation Of Chromosome Separation Positive Regulation Of Aortic Smooth Muscle Cell Differentiation	Polyubiquitin Modification-dependent Protein Binding Canonical NF-kappaB Signal Transduction Positive Regulation Of Proteolysis Flavin Adenine Dinucleotide Catabolic Process VCP-NSFL1C Complex Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Cellular Response To Arsenite Ion Protein Domain Specific Binding Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Mitotic Spindle Disassembly Positive Regulation Of Oxidative Phosphorylation Positive Regulation Of Protein K63-linked Deubiquitination Linear Polyubiquitin Binding Cytoplasm Protein Quality Control BAT3 Complex Binding Positive Regulation Of Protein Deubiquitination Ubiquitin Protein Ligase Binding Positive Regulation Of Mitochondrial Membrane Potential Aggresome Assembly Negative Regulation Of Protein Localization To Chromatin Stress Granule Disassembly Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Deubiquitinase Activator Activity IkappaB Kinase Complex Protein-DNA Covalent Cross-linking Repair Regulation Of Proteolysis Inclusion Body Assembly Derlin-1 Retrotranslocation Complex VCP-NPL4-UFD1 AAA ATPase Complex Regulation Of Protein Localization To Chromatin Regulation Of Protein Deubiquitination Positive Regulation Of Membrane Potential K48-linked Polyubiquitin Modification-dependent Protein Binding ATPase Complex Ubiquitin-modified Protein Reader Activity Cellular Response To Misfolded Protein Transferrin Receptor Binding Anoikis Positive Regulation Of Cellular Respiration Response To Misfolded Protein Positive Regulation Of ATP Biosynthetic Process Retrograde Protein Transport, ER To Cytosol Cellular Response To Arsenic-containing Substance Positive Regulation Of Catabolic Process MHC Class I Protein Binding Regulation Of ATP Biosynthetic Process Ubiquitin-specific Protease Binding Positive Regulation Of T Cell Receptor Signaling Pathway
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