WIPF2 and TCERG1

Number of citations of the paper that reports this interaction (PMID 16055720)
52

Data Source:
BioGRID (pull down)

		WIPF2	TCERG1
Gene Name		WAS/WASL interacting protein family, member 2	transcription elongation regulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton	Nucleus Nucleolus Actin Cytoskeleton
	Molecular Function	Actin Binding Protein Binding	RNA Polymerase II Repressing Transcription Factor Binding RNA Polymerase II Transcription Corepressor Activity Transcription Coactivator Activity Protein Binding Poly(A) RNA Binding Proline-rich Region Binding
	Biological Process	Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APBB1 DNMBP GRB2 ITSN2 NCK2 PFN1 TCERG1 WAS WASL WWOX	52 interactors: ABI1 BARD1 BRD4 CHAF1A CHD3 CPSF6 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 SUMO1 TPM4 U2AF2 WAS WASF2 WBP4 WIPF2 WWOX
Entrez ID		147179	10915
HPRD ID		18304	10393
Ensembl ID		ENSG00000171475	ENSG00000113649
Uniprot IDs		A8MWR2 Q8TF74	O14776
PDB IDs			2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2NNT 3HFH 4FQG
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Regulation Of Cytoskeleton Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Positive Regulation Of Cellular Component Biogenesis Regulation Of Metabolic Process Positive Regulation Of Actin Filament Polymerization Axon Guidance Positive Regulation Of Protein Polymerization Regulation Of Organelle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Actin Nucleation Positive Regulation Of Protein Complex Assembly Axonogenesis Regulation Of Cellular Component Organization Regulation Of Actin Filament Polymerization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Chemotaxis Actin Cytoskeleton Organization Neuron Projection Morphogenesis Actin Filament-based Process Positive Regulation Of Metabolic Process Endocytosis Cell Activation Regulation Of Catalytic Activity Phagocytosis Cell Morphogenesis Involved In Differentiation Vesicle-mediated Transport Anatomical Structure Morphogenesis Fc Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Immune Response-activating Cell Surface Receptor Signaling Pathway Actin Filament Organization Neuron Projection Development Cell Projection Morphogenesis Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Cell Part Morphogenesis Actin Filament-based Movement Positive Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process MRNA 3'-splice Site Recognition Cellular Component Assembly MRNA Splice Site Selection Spliceosomal Complex Assembly Regulation Of RNA Splicing Cellular Macromolecular Complex Assembly Ribonucleoprotein Complex Assembly Cellular Metabolic Process Protein Complex Assembly Cellular Process Positive Regulation Of RNA Splicing Cellular Response To Stress Regulation Of MRNA Processing Actin Polymerization Or Depolymerization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To DNA Damage Stimulus Response To Stress DNA Repair Ribonucleoprotein Complex Biogenesis Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Transcription, DNA-templated Viral Process Phagocytosis Regulation Of Gene Expression Fc Receptor Signaling Pathway RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process MRNA 3'-end Processing Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Metabolic Process Lamellipodium Morphogenesis Rhythmic Process Developmental Process
Tagcloud ?		arg35 arhg5 cbl cblb del digested downscaled doxycycline dyn2 errfi flp hek293 hsp71 hsp7c input irs4 l747 optimisation pc9 ptpra purifications quantities retroviral s752 sos1 sos2 tagged tap usb3b	12p13 12q21 17q11 3q26 5q22 5q32 acgh bac balanced ccnd2 clonality cnas concordant cryptic cytogenetics emp1 evi1 evolving exploratory hidden imbalances karyotypically karyotyping kitlg nf1 platforms recurring submicroscopic unidentified
Tagcloud (Difference) ?		arg35 arhg5 cbl cblb del digested downscaled doxycycline dyn2 errfi flp hek293 hsp71 hsp7c input irs4 l747 optimisation pc9 ptpra purifications quantities retroviral s752 sos1 sos2 tagged tap usb3b	12p13 12q21 17q11 3q26 5q22 5q32 acgh bac balanced ccnd2 clonality cnas concordant cryptic cytogenetics emp1 evi1 evolving exploratory hidden imbalances karyotypically karyotyping kitlg nf1 platforms recurring submicroscopic unidentified
Tagcloud (Intersection) ?