FAM161B and CCDC138

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM161B	CCDC138
Description		FAM161 centrosomal protein B	coiled-coil domain containing 138
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Cytoplasmic Microtubule Microtubule Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Cilium Organization
Pathways
Drugs
Diseases
GWAS		Serum uric acid levels ( 29559957)	Beard thickness ( 26926045) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045)
Interacting Genes		70 interacting genes: ABI2 BICD2 BLOC1S2 BORCS6 CARD9 CBY1 CCDC125 CCDC13 CCDC136 CCDC138 CCDC172 CCDC57 CCDC83 CCDC88B CDR2L CEP55 CEP70 CINP CTNNA3 DDI1 DRC4 EXOSC8 GOLGA2 GOLGA6A GOLGA6L9 GPSM1 HAUS1 HOMER3 HOOK2 HSF2BP ISY1-RAB43 KIAA1328 LZTS1 MAPRE3 MDFI MEIS3 MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NR3C1 OIP5 PICK1 PLAGL2 PNMA1 PPP2R3C RINT1 SH3BP5L SMAD2 SPDEF SRGAP2B STX11 STX1B SYCE1 TEX11 TEX12 TFIP11 TRAF1 TRAF2 TRIM15 TSGA10 TSNAXIP1 TTC23 TTC23L USH1G USHBP1 VPS52 ZC4H2 ZRANB1	11 interacting genes: BOLA2 BOLA2B CDC37 CEP57 FAM161B KRT27 PIBF1 PKN1 TCEANC TRAF3IP3 UBAC1
Entrez ID		145483	165055
HPRD ID		12649	08136
Ensembl ID		ENSG00000156050	ENSG00000163006
Uniprot IDs		Q96MY7	Q96M89
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton Centrosome Identical Protein Binding Microtubule Cytoskeleton Organization Organelle Organization Microtubule-based Process Central Element Protein Binding Cytoskeleton Organization Cytoplasm Microtubule Binding Synaptonemal Complex Assembly Synaptonemal Complex Synaptonemal Complex Organization Cytoskeleton-dependent Intracellular Transport Dynein Light Intermediate Chain Binding Microtubule Nucleation Signaling Adaptor Activity Organelle Transport Along Microtubule Regulation Of Lysosome Size BORC Complex Microtubule Cell Division Organelle Localization Thioesterase Binding Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Golgi Cis Cisterna Vesicle Fusion To Plasma Membrane Regulation Of Endosome Size	Iron-sulfur Cluster Assembly Complex [2Fe-2S] Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding Iron-sulfur Cluster Assembly Cell Redox Homeostasis Protein Maturation Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Binding Negative Regulation Of Prostaglandin Biosynthetic Process HSP90-CDC37 Chaperone Complex
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